思连康联合头孢噻肟钠治疗小儿感染性腹泻的效果分析  

Effect analysis of Siliankang combined with Cefotaxime Sodium in the treatment of infantile infectious diarrhea

作　　者：罗云娇[1] 杜丽江 LUO Yunjiao;DU Lijiang(Department of Infectious Diseases,Kunming Children’s Hospital,Kunming,Yunnan 650000,China)

机构地区：[1]昆明市儿童医院感染一科,云南昆明650000

出　　处：《医药前沿》2022年第26期20-22,共3页Journal of Frontiers of Medicine

摘　　要：目的:分析思连康(双歧杆菌四联活菌片)联合头孢噻肟钠治疗小儿感染性腹泻的效果。方法:回顾性分析2019年1月—2020年12月昆明市儿童医院收治的150例感染性腹泻患儿临床资料,根据治疗方案差异分为常规组和观察组各75例。常规组患儿给予头孢噻肟钠治疗,观察组患儿给予思连康与头孢噻肟钠联合治疗。比较两组患者的治疗有效率、不良反应发生率、免疫指标。结果:常规组患儿的治疗总有效率低于观察组,差异有统计学意义(P<0.05);两组患儿治疗期间不良反应发生率比较,差异无统计学意义(P>0.05);观察组患儿发热症状改善时间、腹泻症状改善时间均短于常规组,差异有统计学意义(P<0.05)。治疗前,两组患儿的免疫指标比较,差异无统计学意义(P>0.05);治疗后,观察组患儿免疫指标优于常规组,差异有统计学意义(P<0.05)。结论:给予感染性腹泻患儿思连康与头孢噻肟钠联合治疗应用效果较好,值得临床应用。Objective To analyze the effect of Siliankang combined with Cefotaxime Sodium in the treatment of infantile infectious diarrhea.Methods The clinical data of 150 children with infectious diarrhea admitted to our hospital from January 2019 to December 2020 were retrospectively analyzed.The children in the routine group were given Cefotaxime Sodium treatment,and the children in the observation group were given the combined treatment of Siliankang and Cefotaxime Sodium,and the application value of the two treatment regimens was statistically compared.Results The treatment effective rate of the children in the routine group was lower than that of the routine group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05),but the observation group had no significant difference in the incidence of adverse reactions(P>0.05).The improvement time of children’s fever symptoms and diarrhea symptoms were significantly lower than those of the routine group(P<0.05).There was no statistical difference in the immune indexes between the two groups before treatment(P>0.05),but the observation after treatment The immune indexes of the children in the group were significantly higher than those in the routine group(P<0.05).Conclusions The combination of Siliankang and Cefotaxime Sodium in the treatment of children with infectious diarrhea can achieve ideal curative effect.

关 键 词：小儿感染性腹泻 思连康 头孢噻肟钠 肠道菌群 

分 类 号：R442.2[医药卫生—诊断学]