^(131)I治疗Graves甲状腺功能亢进的研究进展  

Progress of radioactive iodine therapy(^(131)I)in the treatment of Graves’hyperthyroidism

作　　者：赵岚 胡隽[1] 施燕琴[1] 王菲菲 ZHAO Lan;HU Jun;SHI Yanqin;WANG Feifei(Department of Nuclear Medicine,The First Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,Zhejiang 310003,China)

机构地区：[1]浙江大学医学院附属第一医院核医学科,浙江杭州310003

出　　处：《医药前沿》2022年第26期32-34,共3页Journal of Frontiers of Medicine

摘　　要：Graves甲状腺功能亢进,本质上是一种自身免疫性疾病,其主要特点是患者自身抗体会刺激甲状腺激素受体,导致患者出现甲状腺组织增生或者是甲状腺激素合成、分泌过多现象。Graves甲状腺功能亢进会导致患者的情绪出现一定问题,后续还有可能出现心衰、休克和昏迷等等现象,不利于患者自身的身体健康。当前主要通过药物治疗、放射性碘(^(131)I)治疗和手术切除3种方式对Graves甲状腺功能亢进患者进行治疗。其中,^(131)I治疗在Graves甲状腺功能亢进治疗中较为常见,且应用效果较好。本文主要就^(131)I治疗Graves甲状腺功能亢进的研究进展进行综述。Graves hyperthyroidism,is essentially an autoimmune disease.Its main feature is that patients’autoantibodies will stimulate thyroid hormone receptors,leading to thyroid hyperplasia or excessive thyroid hormone synthesis and secretion.Graves hyperthyroidism will lead to some problems in the patient’s mood,followed by heart failure,shock and coma,which is not conducive to the patient’s own health.At present,Graves hyperthyroidism patients are mainly treated by drug therapy,radioactive iodine therapy(^(131)I)and surgical resection.Among them,131I is more common in the treatment of Graves hyperthyroidism,and the application effect is good.This article mainly reviews the research progress of ^(131)I in the treatment of Graves hyperthyroidism.

关 键 词：综述 放射性核素 碘同位素 甲状腺功能亢进 

分 类 号：R581[医药卫生—内分泌]