Effects of COVID-19 on children with autism  

作　　者：Mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Rawan Alhawamdeh Samara Qaraghuli 

机构地区：[1]Department of Pediatrics,Faculty of Medicine,Tanta University,Tanta 31527,Alghrabia,Egypt [2]Department of Pediatrics,University Medical Center,Arabian Gulf University,King Abdulla Medical City,Arabian Gulf University,Manama 26671,Manama,Bahrain [3]Department of Pediatrics,University Medical Center,Dr.Sulaiman Al-Habib Medical Group,Manama 26671,Manama,Bahrain [4]Department of Medical Microbiology Section,Pathology Department,Salmaniya Medical Complex,Ministry of Health,Kingdom of Bahrain,Manama 12,Manama,Bahrain [5]Department of Microbiology Section,Pathology Department,Irish Royal College of Surgeon,Busiateen 15503,Muharraq,Bahrain [6]Department of Chest Disease,Faculty of Medicine,Tanta University,Tanta 31527,Alghrabia,Egypt [7]Department of Pulmonology,University Medical Center,King Abdulla Medical City,Arabian Gulf University,Manama 26671,Manama,Bahrain [8]Department of Pulmonology,University Medical Center,King Abdulla Medical City,Arabian Gulf University,Dr.Sulaiman Al-Habib Medical Group,Manama 26671,Manama,Bahrain [9]Research and Development Department,Pediatric Occupational Therapist and Neuropsychologist,Genomics Development and Play Center(Genomisc WLL),0000,Manama,Bahrain [10]Research and Development Department,Pediatric Occupational Therapist and Neuropsychologist,Sensory Middle East(SENSORYME DWC-LLC),282228 Dubai,United Arab Emirates [11]Department of Pharmacognosy and Medicinal Plants,Faculty of Pharmacy,Al-Mustansiriya University,Baghdad 14022,Baghdad,Iraq

出　　处：《World Journal of Virology》2022年第6期411-425,共15页世界病毒学杂志

基　　金：We thank the editors and the anonymous referees for their valuable suggestions.

摘　　要：The coronavirus disease 2019(COVID-19)pandemic affects all countries and populations worldwide,significantly impacting people with autism with a high risk of morbidity and mortality due to COVID-19.Approximately 25%of children with autism have an asymptomatic or symptomatic immune deficiency or dysfunction.In addition,they frequently have various comorbid conditions that increase the severity of COVID-19.In addition,severe COVID-19 during pregnancy may increase the risk of autism in the offspring.Furthermore,severe acute respiratory syndrome coronavirus 2 could target human nervous system tissues due to its neurotrophic effects.The COVID-19 pandemic intensely impacts many patients and families in the autism community,especially the complex management of autism-associated disorders during the complete lockdown.During the complete lockdown,children with autism had difficulties coping with the change in their routine,lack of access to special education services,limited physical space available,and problems related to food and sleep.Additionally,children with autism or intellectual disabilities are more liable to be abused by others during the pandemic when the standard community supports are no longer functioning to protect them.Early detection and vaccination of children with autism against COVID-19 are highly indicated.They should be prioritized for testing,vaccination,and proper management of COVID-19 and other infectious diseases.In this review,we discuss the various effects of COVID-19 on children with autism,the difficulties they face,the increased risk of infection during pregnancy,how to alleviate the impact of COVID-19,and how to correct the inequalities in children with autism.

关 键 词：AUTISM ASD Autism Spectrum Disorder CHILDREN COVID-19 Testing VACCINATION NEUROTROPISM SARS-CoV-2 

分 类 号：O17[理学—数学]