辅助剂复合局麻药行周围神经阻滞的应用及发展趋势  

Recent progress of adjuvants to local anesthetics in peripheral nerve block

作　　者：潘志豪 于凯华 王波 鞠衍馨 Pan Zhihao;Yu Kaihua;Wang Bo;Ju Yanxin(Department of Anesthesiology,970th Hospital of the PLA,Yantai 264001,China)

机构地区：[1]解放军第970医院麻醉科,烟台264001

出　　处：《国际医药卫生导报》2022年第23期3355-3358,共4页International Medicine and Health Guidance News

摘　　要：周围神经阻滞(PNB)是临床麻醉和疼痛治疗中常用的方法。单独用局麻药实施PNB,其镇痛维持时间常常难以满足临床需求。临床上通过应用辅助剂复合局麻药可改善镇痛效果,比较常用的有阿片类、α-2肾上腺素能受体激动剂、类固醇等。在应用这些辅助剂时,必须对其作用机制、临床应用优势及局限性等有足够的了解,以便在PNB应用时做出更佳的选择。Peripheral nerve block(PNB)is commonly used in surgical anesthesia and pain treatment.The length of analgesia when a single local anesthetic is used may not last long enough to satisfy clinical need.Adding adjuvants,such as opioids,α-2 agonist,steroids,and so on,may prolong analgesic effect.It is important to acquaintance the action mechanism,advantages,and limitations of these adjuvants to make better clinical choices in PNB.

关 键 词：周围神经阻滞 镇痛 局麻药 辅助剂 

分 类 号：R614[医药卫生—麻醉学]