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作 者:潘建凤 方瑶 颜惠芳 宋一丽 PAN Jian-feng;FANG Yao;YAN Hui-fang;SONG Yi-li(Lishui Branch of Zhongda Hospital Affiliated to Southeast University,Nanjing 211200)
机构地区:[1]东南大学附属中大医院溧水分院,江苏南京211200
出 处:《湖北中医药大学学报》2022年第5期77-79,共3页Journal of Hubei University of Chinese Medicine
基 金:江苏省南京市医学科技发展项目(项目编号:330110502)。
摘 要:目的 观察滋肾育胎丸联合地屈孕酮对先兆流产绒毛下血肿(TASH)患者人绒毛膜促性腺激素(HCG)、出血面积的作用。方法 将我院80例TASH患者随机分为对照组与治疗组各40例。对照组口服地屈孕酮,治疗组口服滋肾育胎丸、地屈孕酮。比较两组临床疗效、中医症候评分、孕酮(P)、绒毛膜促性腺激素(HCG)、雌二醇(E_(2))水平、出血面积、血肿消失时间、阴道出血时间。结果 治疗后,治疗组总有效率显著高于对照组(P<0.05);治疗组血肿消失时间、阴道出血时间短于对照组(P<0.05)。两组治疗后中医症候主症、次症评分、出血面积较治疗前减少,P、HCG、E_(2)水平较治疗前增高;且治疗组中医症候主症、次症评分、出血面积低于对照组,P、HCG、E_(2)水平高于对照组(P<0.05)。结论 滋肾育胎丸联合地屈孕酮能有效提高TASH患者的疗效,降低中医症候积分,增加孕妇性激素水平,缩短血肿消失时间、阴道出血时间。Objective To observe the effect of Zishen Yutai Pills combined with dydrogesterone on human chorionic gonadotropin(HCG)and bleeding area in patients with threatened abortion subchorionic hematoma(TASH). Methods Eighty patients with TASH were randomly divided into control group and treatment group,40 cases in each group. Control group was given oral dydrogesterone,while treatment group was given Zishen Yutai Pills and dydrogesterone orally. The clinical efficacy,TCM symptom score,progesterone(P),chorionic gonadotropin(HCG),estradiol(E_(2))levels,bleeding area,hematoma disappearance time,and vaginal bleeding time were compared between the two groups. Results After treatment,the total effective rate in treatment group was significantly higher than that in control group( P<0.05);the disappearance time of hematoma and vaginal bleeding time in treatment group were shorter than those in control group( P<0.05);the scores of TCM symptoms,secondary symptoms,and bleeding area in both groups decreased compared with those before treatment,which were lower in observation group than in control group;and the levels of P,HCG,and E_(2)increased in both groups,compared with those before treatment,which were higher in observation group than in control group( P<0.05). Conclusion Zishen Yutai Pills combined with dydrogesterone can effectively improve the curative effect of TASH patients,reduce TCM symptom scores,euhance the level of sex hormones in pregnant women,and shorten the disappearance time of hematoma and vaginal bleeding time.
关 键 词:先兆流产 绒毛下出血 出血面积 滋肾育胎丸 地屈孕酮
分 类 号:R271.9[医药卫生—中西医结合]
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