腹主动脉球囊置入术治疗凶险性前置胎盘疗效和对血清AFP、CK表达以及手术结局的影响  

Abdominal Aortic Balloon Implantation in The Treatment of Dangerous Placenta Previa and Its Effect on Serum AFP,CK Expression and Surgical Outcome

作　　者：折开娥[1] 张凌燕[1] 李虹[1] 秦利[1] 吴桂清[1] SHE Kai-e;ZHANG Ling-yan;LI Hong;QIN Li;WU Gui-qing(Obstetrics Department,Shaanxi Provincial People's Hospital,Xi'an,Shaanxi,710068,China)

机构地区：[1]陕西省人民医院产科,陕西西安710068

出　　处：《现代生物医学进展》2022年第19期3759-3762,3728,共5页Progress in Modern Biomedicine

基　　金：陕西省重点研发计划项目(2020SF-050)。

摘　　要：目的:探讨与分析腹主动脉球囊置入术治疗凶险性前置胎盘疗效和对血清AFP、CK表达以及手术结局的影响。方法:将2019年1月到2021年12月在本院住院剖宫产的凶险性前置胎盘产妇153例作为研究对象,对照组48例为剖宫产术,研究组105例为剖宫产术前行腹主动脉球囊置入术。检测两组血清甲胎蛋白(AFP)、肌酸激酶(CK)表达水平,记录手术结局。结果:所有产妇都顺利完成治疗与分娩,无死亡产妇与新生儿。研究组的产后出血量较对照组低(P<0.05),而产前出血量在两组对比无差异(P>0.05)。两组新生儿体重对比无差异(P>0.05),研究组的1 min Apgar评分、5 min Apgar评分较对照组高,而呼吸窘迫综合征发生率较对照组低(P<0.05)。两组手术后3 d的血清AFP与CK含量明显低于术前,研究组也显著低于对照组(P<0.05)。研究组出院时的满意度为94.29%,明显高于对照组的79.17%(P<0.05)。结论:腹主动脉球囊置入术治疗凶险性前置胎盘能促进降低血清AFP与CK含量,能促进产妇与新生儿恢复健康,提高产妇的满意度。Objective:To explore and analysis the efficacy of abdominal aortic balloon implantation in the treatment of dangerous placenta previa and its effect on serum AFP,CK expression and surgical outcome.Methods:A total of 153 dangerous placenta previa patients hospitalized for cesarean section from January 2019 to December 2021 were included as study subjects,48 patients in the control group had cesarean section,and 105 patients in the study group had abdominal aortic balloon placement before cesarean section.The serum alpha-fetoprotein(AFP) and creatine kinase(CK) expression levels were detected in the two groups,and the surgical outcomes were recorded.Results:All mothers were completed the treatment and delivery successfully,and there were no deaths of mothers and newborns.The amount of postpartum hemorrhage in the research group were significantly lower than that in the matched group(P<0.05),while there were no significant difference in the amount of prenatal hemorrhage compared between the two groups(P>0.05).There were no significant difference in neonatal weight compared between the two groups(P>0.05).The 1 min Apgar score and 5 min Apgar score in the research group were significantly higher than those in the matched group(P<0.05),and the incidence of respiratory distress syndrome were significantly lower than that in the matched group(P<0.05).The serum AFP and CK levels at 3d after operation in the two groups were significantly lower than those before operation(P<0.05),and the research group were also significantly lower than that in the matched group(P<0.05).The satisfaction rates at discharge in the research group were 94.29 %,which were significantly higher than79.17 % in the matched group(P<0.05).Conclusion:Abdominal aortic balloon implantation in the treatment of dangerous placenta previa can promote the reduction of serum AFP and CK levels,promote the recovery of maternal and neonatal health,and improve maternal satisfaction.

关 键 词：腹主动脉球囊置入术 凶险性前置胎盘 甲胎蛋白 肌酸激酶 

分 类 号：R714.462[医药卫生—妇产科学]