川崎病合并巨大冠状动脉瘤的临床研究进展  

Advances in Kawasaki disease combined with giant coronary aneurysm

作　　者：王露(综述) 刘晓燕(审校)[1] Wang Lu;Liu Xiaoyan(Department of Cardiology,Children′s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Developmental Disorder,National Clinical Research Center for Child Health and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院心血管内科,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医学研究中心,儿童发育重大疾病国家国际科技合作基地,儿科学重庆市重点实验室,400014

出　　处：《国际儿科学杂志》2022年第10期658-662,共5页International Journal of Pediatrics

摘　　要：川崎病冠状动脉病变已成为部分国家、地区常见的儿童获得性心血管疾病之一,巨大冠状动脉瘤是川崎病冠状动脉病变中的严重类型,后期完全恢复的可能性较小,其心血管事件发生率和病死率均明显升高。巨大冠状动脉瘤患儿进入成年期后有较高的心血管疾病发病风险,而且儿童期巨大动脉瘤与青壮年心源性猝死及成年后冠状动脉粥样硬化的发生密切相关,对患儿的长期预后和生活质量产生严重影响。该文就川崎病合并巨大冠状动脉瘤的临床特点及预后作一综述。Kawasaki disease coronary artery lesions have become one of the common acquired cardiovascular diseases in children in some countries and regions.Giant coronary artery aneurysms are a severe type of Kawasaki disease coronary artery lesion with less likelihood of complete recovery at a later stage,and their cardiovascular event rate and mortality are significantly higher than those of other children with Kawasaki disease.Children with giant coronary aneurysms are at higher risk of cardiovascular disease in adulthood and are closely associated with sudden cardiac death in young adulthood and the development of coronary atherosclerosis in adulthood,with serious implications for the long-term prognosis and quality of life of the child.This article reviews the clinical features and prognosis of Kawasaki disease combined with giant coronary aneurysms.

关 键 词：川崎病 巨大冠状动脉瘤 临床特点 预后 随访 

分 类 号：R725.4[医药卫生—儿科]