莪术及其主要成分的药理作用研究进展  

Research progress on pharmacological effects of Curcumae Rhizoma and its main chemical compositions

作　　者：魏巍 王冰瑶[2] WEI Wei;WANG Bingyao(Increasepharm(Tianjin)Institute Co.,Ltd.,Tianjin 300382,China;Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]盈科瑞(天津)创新医药研究有限公司,天津300382 [2]天津中医药大学,天津301607

出　　处：《药物评价研究》2022年第10期2154-2160,共7页Drug Evaluation Research

摘　　要：莪术是传统中药,具有行气破血、消积止痛的功效。莪术所含化学成分众多,挥发油类和姜黄素类等化合物为其主要活性成分。现代药理研究表明莪术具有抗肿瘤、心脑血管系统保护、免疫调节、保肝、镇痛抗炎、抗病毒、抑菌、降血糖、抗氧化等作用。通过查阅整理近年来国内外有关莪术化学成分研究和药理活性研究文献,对其主要药理作用等进行了综述,以期为莪术的药物开发及临床应用提供依据。Curcumae Rhizoma is a traditional Chinese medicine,with the effect of breaking the blood flow and relieving pain.Curcumae Rhizoma contains many chemical compositions,including volatile oils and curcumin compounds for its main active compositions.Modern pharmacological studies show that Curcumae Rhizoma has the effects of anti-tumor,cardiovascular and cerebrovascular system,immune system,liver protection,anti-inflammatory,anti-virus and bacteriostasis,hypoglycemic and antioxidant activities.This article summarizes the research progress on pharmacology of Curcumae Rhizoma in recent years for providing a basis for Curcumae Rhizoma drug development and clinical application.

关 键 词：莪术 挥发油 姜黄素 药理作用 抗肿瘤 保肝 

分 类 号：R285.5[医药卫生—中药学]