白藜芦醇化学成分及抗癌药理作用的研究进展  

Research Progress on Chemical Constituents and Anticancer Pharmacological Effects of Resveratrol

作　　者：杨春苗 杨东生 萨仁高娃 杜娟 Yang Chunmiao;Yang Dongsheng;SaRen Gaowa;Du Juan(College of Pharmacy and Food Science,Zhuhai College of Science and Technology,Zhuhai 519041,China)

机构地区：[1]珠海科技学院药学与食品科学学院,广东珠海519041

出　　处：《广东化工》2022年第21期108-110,共3页Guangdong Chemical Industry

基　　金：广东普通高校特色创新类项目(自然科学类)基金(2021KTSCX173);吉林大学珠海学院基金项目(2019XJCQ005);珠海科技学院创新能力培育工程项目(2020XJCQ018);珠海科技学院博士提升计划。

摘　　要：白藜芦醇(Resveratrol,RES)是一种天然存在的多酚类植物抗毒素,主要存在于葡萄、虎杖和花生中。白藜芦醇具有抗癌、抗衰老、抗氧化、抗增殖、保护心脏和提高免疫力的作用,在癌症或自身免疫性疾病的治疗中白藜芦醇得到了广泛的关注。本文对白藜芦醇的化学成分及主要抗癌机制的研究进展加以综述,为癌症的预防、治疗和新药的开发提供理论依据。Resveratrol is a naturally occurring polyphenolic phytoalexin with significant anticancer activity,Which is mainly found in grapes,berries and peanuts.Moreover,it has been reported that resveratrol has a variety of effect on Anti-aging,cardioprotective,antioxidant,anti-proliferative,pro-apoptotic and improve immunity,it has received extensive attention in the treatment of cancer or autoimmune diseases.This article reviews the research progress on the chemical constituents and main anticancer mechanism of resveratrol,In order to provide a theoretical basis for cancer prevention,treatment and development of new drugs.

关 键 词：白藜芦醇 癌症干细胞 抗癌 致癌基因 生物学机制 

分 类 号：TQ[化学工程]