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作 者:刘青 黄芳 Liu Qing;Huang Fang(Shanghai JAKA Biotech Co.,Ltd.,Shanghai 201506,China)
出 处:《广东化工》2022年第22期76-78,共3页Guangdong Chemical Industry
摘 要:以侧柏叶提取物、姜根提取物、红车轴草叶提取物和艾叶提取物的复合物(命名为密源植萃)为研究对象,利用人毛乳头细胞(HDPCs)和临床方法评测密源植萃的防脱发功效。HDPCs测试结果表明,密源植萃可显著增强HDPCs的自噬活性,促进HDPCs分泌血管内皮生长因子(VEGF)。人体试用结果表明,外用含2.0%密源植萃的精华液4周、8周、12周后,脱发数量均明显减少,脱发数量减少率分别为19.9%、37.8%和53.8%。试用过程中,受试者均未出现不良反应。Anti-hair loss effect of a mixture comprising arborvitae tops extract,ginger root extract,clover leaf extract,and mugwort leaf extract(named Hairdian AP)was evaluated using human dermal papilla cells(HDPCs)and a clinical method.The results showed that Hairdian AP significantly enhanced autophagy of HDPCs,and promoted secretion of vascular endothelial growth factor(VEGF)by HDPCs.After topically application of an essence containing 2.0%of Hairdian AP for 4,8,and 12 weeks,the number of shedding hairs decreased significantly.The reduction rates were 19.9%,37.8%,and 53.8%,respectively.During the trial,no adverse reaction occurred.
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