临床药师干预对骨科Ⅰ类切口围术期抗菌药物合理用药的影响  

Effect of Clinical Pharmacist Intervention on Rational Use of Antibiotics during Perioperative Period of Orthopaedic Class Ⅰ Incision

作　　者：翟亚业[1] 秦晓彬[1] 李含[1] 李森[1] 张超远[1] ZHAI Yaye;QIN Xiaobin;LI Han;LI Sen;ZHANG Chaoyuan(Department of Orthopaedics,Nanyang Central Hospital,Nanyang 473009,Henan,China)

机构地区：[1]南阳市中心医院骨三科,河南南阳473009

出　　处：《中国药物滥用防治杂志》2022年第10期1408-1411,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:分析临床药师干预对骨科Ⅰ类切口围术期抗菌药物合理用药的影响。方法:收集2019年2月—2022年2月该院收治的骨科Ⅰ类切口进行手术的60例患者的病历资料,根据临床药师是否干预分为对照组和观察组,各30例。对照组采用传统用药方式,观察组采用临床药师干预后给药,比较两组给药时机、预防给药疗程以及不合理用药情况。结果:观察组术前30 min—2 h合理用药占比高于对照组,差异有统计学意义(P<0.05);观察组预防给药疗程1天<给药时间<2天占比高于对照组,预防给药疗程>2天时占比低于对照组,差异有统计学意义(P<0.05);观察组术后用药时间过长、用药无指征、术前不用术后用占比少于对照组,差异有统计学意义(P<0.05)。结论:临床药师干预可促使给药时机更加合理,且可减少用药时间及不合理用药情况。Objective: To analyze the effect of clinical pharmacist intervention on the rational use of antibiotics during perioperative period of orthopedic class I incision. Methods: The clinical data of 60 patients undergoing orthopedic type I incision surgery in our hospital from February 2019 to February 2022 were collected and divided into control group and observation group according to whether clinical pharmacists intervened, with 30 cases in each group. The control group was treated with traditional medication, while the observation group was treated with clinical pharmacist intervention. The medication timing, preventive medication course and irrational drug use were compared between the two groups. Results: The observation group’s proportion of rational drug use 30 min-2 h before operation compaered with the control group was higher, with a statistical significant difference(P<0.05).The proportion of the observation group with a course of preventive administration for 1 day < administration time < 2 days compared with the control group was higher, and the proportion of the preventive administration course of more than 2 days compared with the control group was lower, with a statistical significant difference(P<0.05).The observation group’s postoperative medication time too long, no indication for medication, and the proportion of patients who did not use before and after surgery compared with the control group was less, with a statistical significant difference(P<0.05). Conclusion: The intervention of clinical pharmacists can make the administration time more reasonable,reduce the medication time, and improve the medication and irrational drug use.

关 键 词：临床药师 骨科Ⅰ类切口 围术期 抗菌药物 合理用药 

分 类 号：R969.3[医药卫生—药理学]