呼吸科多重耐药菌感染的病原菌及易感因素的研究  

Study on the Pathogens and Susceptibility Factors of Multidrug-resistant Bacterial Infection in Respiratory Unit

作　　者：薛茜[1] XUE Qian(Liangxiang Hospital,Fangshan District,Beijing 102488,China)

机构地区：[1]北京市房山区良乡医院,北京102488

出　　处：《中国医药指南》2022年第34期25-28,共4页Guide of China Medicine

摘　　要：目的 分析呼吸科多重耐药菌感染的病原菌和易感因素。方法 选择我院呼吸科患者为研究对象,均在2020年1月至2021年1月开始检测,共检测200例患者,分析200例患者住院期间多重耐药菌检出状况进行分析。结果 200例患者中有102例患者发生感染,感染发生率为51.00%。一共分离、培养病原菌112株。耐甲氧西林金黄葡萄球菌占比为6.25%,耐万古霉素肠球菌占比为2.68%,产超广谱性β-内酰胺酶病菌占比为31.25%,耐碳青霉烯肠杆菌科病菌占比为22.32%,耐碳青霉烯类鲍曼不动杆菌占比为16.07%,多重耐药铜绿假单胞菌占比为21.43%。感染患者和未感染患者在年龄、住院时间、应用呼吸机、合并其他疾病以及侵入性操作方面均存在差异性(P <0.05)。患者年龄较大、住院时间较长、合并其他疾病以及应用呼吸机、侵入性治疗等均为呼吸科住院患者发生多重耐药菌感染的易感因素。住院时间、应用呼吸机、合并其他疾病以及侵入性操作方面均为呼吸科多重耐药菌易感因素,(P <0.05)。结论 对呼吸科多重耐药菌感染需要引起高度重视,积极分析其病原菌以及易感因素,及时采取有效解决措施,降低多重耐药菌感染发生率。Objective To analyze the pathogens and susceptibility factors of multidrug-resistant bacterial infection respiratory unit infections.Methods The respiratory patients of our hospital were selected,tested from January 2020 to January 2021,200 patients were tested,and 200 patients were analyzed.Results One hundred and two of 200 patients had infection in 51.00%.A total of 112 pathogenic bacterial strains were isolated and cultured.Methicillin-resistant Staphylococcus aureus was 6.25%,vancomycin-resistant enterococci 2.68%,ultra-broad spectrumlactamase 31.25%,carbapenem-resistant Enterobacteriaceae 22.32%,carbapenem-resistant A.baumannii 16.07%,and multidrug-resistant P.aeruginosa 21.43%.Infected and uninfected patients differ in age,length of stay,ventilator application,combining other diseases,and invasive procedures(P<0.05).Older age,longer hospitalization time,other diseases,application of ventilator and invasive treatment were all predisposing factors for inpatients in the respiratory department.Hospitalization time,ventilator application,other diseases and invasive operations were multisusceptible to respiratory antibiotics(P<0.05).Conclusion Pay great attention to multidrug-resistant bacterial infection in respiratory unit,actively analyze their pathogens with susceptibility factors,and take effective measures to reduce the incidence of multidrugresistant bacterial infection.

关 键 词：呼吸科 多重耐药菌感染 病原菌 易感因素 分析 

分 类 号：R181[医药卫生—流行病学]