病理性近视患者中医体征特点调查研究  

Investigation on Characteristics of Traditional Chinese Medicine Signs of Patients with Pathological Myopia

作　　者：高延娥[1] 刘德政 蒋文君[1] 王淑雅[1] 李忠恩[1] 毕宏生[1] 王兴荣[1] GAO Yan’e;LIU Dezheng;JIANG Wenjun;WANG Shuya;LI Zhongen;BI Hongsheng;WANG Xingrong(Eye Hospital Affiliated to Shandong University of Traditional Chinese Medicine/Shandong Academy of Eye Disease Prevention and Therapy/Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Eye Disease,Jinan 250002,China;Zaozhuang Municipal Hospital in Shandong Province,Zaozhuang 277100,China)

机构地区：[1]山东中医药大学附属眼科医院/山东省眼病防治研究院/山东省中西医结合眼病防治重点实验室,山东济南250002 [2]山东枣庄市立医院,山东枣庄277100

出　　处：《山东中医杂志》2022年第12期1285-1291,共7页Shandong Journal of Traditional Chinese Medicine

基　　金：国家重点研发计划项目(编号:2021YFC2702103);山东省中西医结合专病防治项目(编号:YXH2019ZXY001);山东省中医药科技项目(编号:M-2022165)。

摘　　要：目的:调查研究病理性近视患者的中医体征特点。方法:选择病理性近视患者125例作为病理性近视组,同时招募正视及低度近视大学生志愿者145例作为对照组。采用独立样本t检验分析两组中医体质、证候类型差异,并分析病理性近视组证型与体质的相关性,以及近视黄斑病变等级与不同证型、体质的相关性。结果:①两组中医体质及证型分布比较,差异有统计学意义(P<0.05)。病理性近视组中医证型以脾虚气弱证(58.40%)、肝肾亏虚证(28.80%)最为多见,对照组均为阴阳平衡状态;病理性近视组偏颇体质以阳虚质(26.40%)、气虚质(12.80%)为主,这两种体质患者占该组的比例均高于对照组相应体质人群占比(P<0.05)。②病理性近视组18~40岁患者证型以脾虚气弱证(73.33%)居多,偏颇体质以气虚质居多(24.44%);41~85岁患者证型以脾虚气弱证(50.00%)、肝肾亏虚证(40.00%)居多,偏颇体质以阳虚质(36.25%)居多。男性病理性近视患者偏颇体质以阳虚质(18.18%)、气虚质(12.73%)多见;女性病理性近视患者偏颇体质以阳虚质(32.86%)居多。③病理性近视组患者近视黄斑病变分级状况为:C2级84眼,C3级9眼,C4级32眼,其中以C2级(67.20%)最多见。对照组近视黄斑病变分级均为C0级。病理性近视组脾虚气弱证患者近视黄斑病变以C2级(76.71%)居多,肝肾亏虚证患者近视黄斑病变以C4级(50.00%)居多。④平和质、阳虚质、气虚质病理性近视患者近视黄斑病变均以C2级最为多见。结论:病理性近视患者与正视及低度近视人群的中医体质、证型分布存在差异,病理性近视患者偏颇体质以阳虚质、气虚质居多,中医证型以脾虚气弱证、肝肾亏虚证多见;不同性别、年龄的病理性近视患者证型、体质存在差异;证型与近视黄斑病变分级具有一定相关性。Objective:To investigate the characteristics of traditional Chinese medicine(TCM)signs of patients with pathological myopia.Methods:A total of 125 patients with pathological myopia were enrolled into the study as the pathological myopia group.At the same time,145 undergraduate volunteers with emmetropia or low myopia were enrolled as the control group.The independent t test was used to analyze the differences in TCM constitution and syndrome types between the pathological myopia group and the control group.In the pathological myopia group,the correlation between syndrome types and constitution,and that among the grade of myopic macular degeneration(MMD),syndrome types and constitution were analyzed.Results:①The differences in distribution of TCM syndrome types and constitution between the two groups were statistically significant(P<0.05).In the pathological myopia group,the most common TCM syndrome types were spleen deficiency and qi weakness syndrome(58.40%),and liver and kidney deficiency syndrome(28.80%),while patients in the control group were in a balance state of yin and yang.The biased constitution of the pathological myopia group was dominated by yang deficiency constitution(26.40%)and qi deficiency constitution(12.80%),and the proportion of these two kinds of constitution in the pathological myopia group was higher than that in the control group(P<0.05).②In the patients aged 18 to 40 years,for the syndrome types,those with spleen deficiency and qi weakness syndrome(73.33%)were in a majority,and for the biased constitution,those with qi deficiency constitution(24.44%)took the largest proportion.In the patients aged 41 to 85 years,for the syndrome types,those with spleen deficiency and qi weakness syndrome(50.00%)and those with liver and kidney deficiency syndrome(40.00%)were in a majority,and for the biased constitution,those with yang deficiency constitution(36.25%)took the largest proportion.The biased constitution of male patients was dominated by yang deficiency constitution(18.18%)and qi deficien

关 键 词：病理性近视 体质 阳虚质 气虚质 证型 脾虚气弱证 肝肾亏虚证 近视黄斑病变等级 

分 类 号：R246.82[医药卫生—针灸推拿学]