清肝健脾法治疗妊娠期肝内胆汁淤积症的临床疗效及对围产儿预后的影响  

Clinical efficacy of Qinggan Jianpi method in the treatment of intrahepatic cholestasis of pregnancy and its effect on perinatal prognosis

作　　者：张庆勤 Zhang Qingqin(Department of Obstetrics,Nanhai Maternal and Child Health Hospital,Nanhai District,Foshan City,Foshan 5280000,China)

机构地区：[1]佛山市南海区南海妇幼保健院产科,广东佛山5280000

出　　处：《实用妇科内分泌电子杂志》2022年第16期78-81,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的观察清肝健脾法治疗妊娠期肝内胆汁淤积症(ICP)的临床疗效及对围产儿预后的影响。方法选取本院收治的ICP患者60例为研究对象,根据随机抽签法分为两组,每组30例。对照组采用常规西医治疗,研究组在此基础上采用清肝健脾法治疗。比较两组临床疗效及对围产儿预后的影响。结果治疗前,两组各项肝功能指标水平比较,差异无统计学意义(P>0.05);治疗后,研究组各项肝功能指标水平均低于对照组,差异有统计学意义(P<0.05)。治疗前,两组瘙痒评分比较,差异无统计学意义(P>0.05);治疗后,研究组瘙痒评分低于对照组,差异有统计学意义(P<0.05)。研究组治疗总有效率为96.67%,高于对照组的80.00%,差异有统计学意义(P<0.05)。研究组围产儿不良结局发生率为10.00%,低于对照组的33.33%,差异有统计学意义(P<0.05)。结论ICP患者采用清肝健脾法治疗的效果理想,可改善肝功能,减轻瘙痒症状,还可改善围产儿预后,值得临床推广使用。Objective To observe the clinical effect of Qinggan Jianpi method in the treatment of intrahepatic cholestasis of pregnancy(ICP)and its effect on perinatal prognosis.Methods A total of 60 patients with ICP admitted to our hospital were selected as the research objects and were divided into two groups according to the random lottery method,with 30 cases in each group.The control group was treated with conventional western medicine,and the study group was treated with Qinggan Jianpi method on this basis.The clinical efficacy and the effect on perinatal prognosis were compared between the two groups.Results Before treatment,there were no significant differences in the levels of liver function indexes between the two groups(P>0.05);after treatment,the levels of liver function indexes in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in pruritus score between the two groups(P>0.05);after treatment,the pruritus score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).The total effective rate of the study group was 96.67%,which was higher than 80.00% of the control group,and the difference was statistically significant(P<0.05).The incidence of perinatal adverse outcomes in the study group was 10.00%,which was lower than 33.33% in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of clearing liver and strengthening spleen in the treatment of ICP is ideal,which can improve liver function,relieve pruritus and perinatal prognosis.It is worthy of clinical application.

关 键 词：清肝健脾法 妊娠期 肝内胆汁淤积症 围产儿预后 

分 类 号：R714.255[医药卫生—妇产科学]