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作 者:张小魏 Zhang Xiaowei(Department of Obstetrics,Binhai People's Hospital,Yancheng 224500,China)
出 处:《实用妇科内分泌电子杂志》2022年第15期52-55,共4页Electronic Journal of Practical Gynecological Endocrinology
摘 要:目的探讨不同抗生素治疗产后盆腔腹膜炎的有效性。方法选取50例产后盆腔腹膜炎患者,根据随机数字表法分为对照组与研究组,每组25例。对照组采用头孢曲松治疗,研究组采用头孢呋辛治疗。对比两组治疗前后炎性因子指标、临床疗效及不良反应发生情况。结果治疗前,两组患者白细胞计数(WBC)、C反应蛋白(CRP)、白介素-6(IL-6)指标对比,差异无统计学意义(P>0.05);治疗后,研究组患者WBC、CRP及IL-6指标均低于对照组,差异具有统计学意义(P<0.05)。研究组治疗总有效率为92.00%,对照组治疗总有效率为84.00%,对比差异无统计学意义(P>0.05)。研究组不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论头孢曲松与头孢呋辛在产后盆腔腹膜炎治疗中均能够发挥较好的治疗作用,但后者抑制炎性因子作用更明显,安全性更高,临床医师可根据患者具体情况合理使用药物。Objective To investigate the effectiveness of different antibiotics in the treatment of postpartum pelvic peritonitis.Methods 50 patients with postpartum pelvic peritonitis were selected and divided into control group and study group according to the random nximber table method,25 cases in each group.The control group was treated with ceftriaxone,and the study group was treated with cefuroxime.Inflammatory factors,clinical efficacy and adverse reactions were compared between the two groups before and after treatment.Results Before treatment,there were no significant differences in white blood cell count(WBC),C-reactive protein(CRP)and interleukin-6(IL-6)between the two groups(P>0.05).After treatment,the indexes of WBC,CRP and IL-6 in the study group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of the study group was 92.00%,and the total effective rate of the control group was 84.00%,and the difference was not statistically significant(P>0.05).The incidence of adverse reactions in study group was significantly lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion Ceftriaxone and cefuroxime can both play a good therapeutic role in the treatment of postpartum pelvic peritonitis,but the latter has a more obvious effect on the inhibition of inflammatory factors and higher safety.Clinicians can use the drugs rationally according to the specific situation of patients.
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