SinCHERS-HPLC-MS/MS法检测环境固体样品中20种全氟和多氟类化合物  

Analysis of 20 per-and polyfluoroalkyl substances in environmental solid samples by SinCHERS-high performance liquid chromatography-electrospray ionization-mass spectrometry

作　　者：张梦 邵秀清 王佩[1,3] 吕永龙 史雅娟[1,2] 王聪 周云桥[1,2] 张少玉 ZHANG Meng;SHAO Xiuqing;WANG Pei;LYU Yonglong;SHI Yajuan;WANG Cong;ZHOU Yunqiao;ZHANG Shaoyu(State Key Laboratory of Urban and Regional Ecology,Research Centre for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing,100085,China;University of Chinese Academy of Sciences,Beijing,100049,China;College of the Environment&Ecology,Xiamen University,Xiamen,361102,China;Anybond(Tianjin)Co.,Ltd,Tianjin,300134,China)

机构地区：[1]中国科学院生态环境研究中心,北京100085 [2]中国科学院大学,北京100049 [3]厦门大学,环境与生态学院,厦门361102 [4]天津安邦键合科技有限公司,天津300134

出　　处：《环境化学》2022年第11期3514-3524,共11页Environmental Chemistry

基　　金：中国科学院国际大科学计划培育项目(121311KYSB20190029);国家自然科学基金(717611470001,41977360);国家重点研发计划项目(2018YFC1801103)资助。

摘　　要：建立了SinCHERS-高效液相色谱串联质谱(HPLC-MS/MS)技术的土壤样品中20种全氟和多氟类化合物(Per-and polyfluoroalkyl substances,PFAS)的萃取、净化和检测方法.采用无水硫酸镁、层间距为20 nm的石墨化碳黑、HLB离子交换材料的组合作为SinCHERS前处理净化小柱的净化填料,使用HPLC-MS/MS检测,内标法定量.目标化合物的方法检出限在0.48—2.31 ng·g^(−1)dw(干重)之间,方法回收率在71.0%—110.6%之间,标准偏差在2.7%—13.4%之间.相较于固相萃取(SPE)样品前处理流程,SinCHERS净化方法大大缩短了样品中污染物萃取净化的时间,降低了经济成本,优化了某些长链PFAS的萃取效率,且具有相对较高的稳定性.提高了在16 min内同时检测20种PFAS的检测效率,为环境中PFAS评估提供更为方便的检测方法以得到有效的基础数据.A method for the extraction,purification,and determination of 20 per-and polyfluoroalkyl substances(PFAS)in environmental solid samples by SinCHERS-high liquid chromatography-electrospray ionization-mass spectrometry(HPLC-MS/MS)was established.The combination of anhydrous magnesium sulfate,graphitized carbon black with interlayer spacing of 20 nm,and HLB ion exchange material was used as the cleanup sorbents in SinCHERS cartridge.20 PFAS were determined by HPLC-MS/MS using internal standard method.The method detection limit of the target compounds were 0.48—2.31 ng·g^(−1) dw,the recoveries were 71.0%—110.6%,and the standard deviations were 2.7%—13.4%.Compared with SPE sample pretreatment,this method is more time saving,more economical,and more stable.It also improves the recoveries of some longchain PFAS.It provides a more convenient detection method for PFAS evaluation in the environment to obtain effective basic data.

关 键 词：SinCHERS 高效液相色谱串联质谱 全氟和多氟类化合物. 

分 类 号：X833[环境科学与工程—环境工程]