重庆地区11284例患者生殖道沙眼衣原体与解脲脲原体检出情况分析  

The analysis on the detection of chlamydia trachomatis and ureaplasma urealyticum in 11284 patients in Chongqing area

作　　者：刘孟涓 李秋红[1] 李春莉[1] LIU Mengjuan;LI Qiuhong;LI Chunli(Department of Clinical Laboratory,Chongqing Health Center for Women and Children,Women and Children's Hospital of Chongqing Medical University,Chongqing 401147,China)

机构地区：[1]重庆市妇幼保健院·重庆医科大学附属妇女儿童医院检验科,重庆401147

出　　处：《西部医学》2022年第12期1863-1867,共5页Medical Journal of West China

摘　　要：目的分析近五年重庆地区成年患者生殖道沙眼衣原体(CT)、解脲脲原体(UU)感染情况及特征,为临床防治提供参考依据。方法选取2017年1月~2021年12月于重庆市妇幼保健院就诊的11284例患者样本,包括生殖道拭子、精液和前列腺液标本,采用实时荧光定量PCR技术同时检测CT、UU两种病原体,并对检测结果进行统计学分析。结果CT、UU及CT+UU混合感染的总体检出率分别为4.51%(509/11284)、43.31%(4887/11284)、2.75%(310/11284)。UU的检出率显著高于CT(P<0.001)。女性的各项检出率均显著高于男性(均P<0.001)。不同年龄段患者中,18~<30岁低育龄组患者的各项检出率均显著高于30~45岁高育龄组患者(均P<0.001)。不同类型样本中,男性尿道分泌物CT、UU检出率显著高于精液标本(均P<0.001)。不同诊断的男性患者中,泌尿生殖道感染患者CT、UU检出率均显著高于健康查体者(均P<0.05),而不育症患者UU检出率显著高于健康查体者(P<0.05)。不同诊断的女性患者中,泌尿生殖道感染患者CT检出率显著高于健康查体者(P<0.05),而不孕症患者CT、UU检出率均显著高于健康查体者(均P<0.05)。此外,重庆地区UU的冬季检出率显著高于夏季(P<0.05),而CT的秋季检出率也显著高于夏季(P<0.05)。结论近年来重庆地区成年患者生殖道CT、UU感染呈逐年加重趋势,女性感染率显著高于男性;临床上可将CT、UU作为生殖道感染和不孕不育患者的常规筛查指标,同时应重视无症状患者的隐匿感染,加强季节性预防,减少性传播疾病的感染和传播。Objective To analyze the infection status and characteristics of chlamydia trachomatis(CT)and Ureaplasma urealyticum(UU)in adult patients in Chongqing area in recent five years,and provide reference for clinical prevention and treatment.Methods From January 2017 to December 2021,samples(including genital swab,semen and prostatic fluid)from 11284 patients admitted to Chongqing Health Center for Women and Children were detected by real-time quantitative PCR for CT and UU,and the results were statistically analyzed.Results The overall detection rates of CT,UU and CT+UU mixed infection were 4.51%(509/11284),43.31%(4887/11284)and 2.75%(310/11284),respectively.The detection rate of UU was significantly higher than that of CT(P<0.001).The detection rates of all items in females were significantly higher than those in males(all P<0.001).In different age groups,the detection rates of the low reproductive age group of 18~<30 years old were significantly higher than those of the high reproductive age group of 30~45 years old(all P<0.001).Among different types of samples,the detection rates of male urethral secretion were significantly higher than those of semen(both P<0.001).Among male patients with different diagnoses,the detection rates of CT and UU in patients with genitourinary tract infection were significantly higher than those in healthy subjects(both P<0.05),and the detection rate of UU in infertile patients was significantly higher than that in healthy subjects(P<0.05).Among female patients with different diagnoses,the detection rate of CT in patients with genitourinary tract infection was significantly higher than that in healthy subjects(P<0.05),and the detection rates of CT and UU in infertile patients were significantly higher than those in healthy subjects(both P<0.05).In addition,the detection rate of UU in winter was significantly higher than in summer(P<0.05),while the detection rate of CT in autumn was significantly higher than that in summer(P<0.05).Conclusion In recent years,CT and UU infection of reprod

关 键 词：重庆地区 沙眼衣原体 解脲脲原体 生殖道感染 

分 类 号：R446.5[医药卫生—诊断学]