UF-1000i全自动尿液分析仪检测小红细胞比例用于筛查肾小球肾炎性血尿的临床意义  

Clinical significance of small red blood cell percentage detected by UF-1000i automatic urine analyzer for diagnosing glomerulonephritis hematuria

作　　者：郑建波 Zheng Jianbo(Department of Clinical Laboratory,Cancer Hospital of Putian City,Putian 351100,Fujian,China)

机构地区：[1]莆田市肿瘤医院检验科,福建莆田351100

出　　处：《实用检验医师杂志》2022年第3期280-282,共3页Chinese Journal of Clinical Pathologist

摘　　要：目的评估UF-1000i全自动尿液分析仪检测小红细胞比例(UF-sRBC%)并用于鉴别血尿的临床意义。方法选择2018年7月—2021年6月莆田市肿瘤医院收治的126例血尿患者作为研究对象,包括61例肾小球肾炎性(GN)血尿和65例非肾小球肾炎性(NGN)血尿。分析患者尿液样本,显微镜检查尿液中异形红细胞比例(dRBC%);采用UF-1000i全自动尿液分析仪分析UF-sRBC%。采用Pearson相关性分析方法考察dRBS%与UF-sRBC%的相关性。计算受试者工作特征曲线下面积(AUC),评估上述指标对GN血尿的诊断价值。结果GN组的dRBC%和UF-sRBC%均明显高于NGN组〔dRBC%:(33.4±24.5)%比(3.1±2.8)%,UF-sRBC%:(35.8±28.9)%比(14.6±13.6)%,均P<0.05〕。Pearson相关性分析显示,dRBC%与UF-sRBC%呈显著正相关(r=0.678,P<0.0001)。dRBC%和UF-sRBC%的AUC分别为0.774、0.747,敏感度分别为75.6%、72.3%,特异度分别为75.4%、76.7%,最佳截断值分别为6.9%、29.3%。结论UF-sRBC%与dRBC%对GN具有相似的诊断价值。UF-sRBC%检测操作简便,可用于GN的初步筛查和鉴别。Objective To evaluate the clinical significance of small red blood cell percentage(UF-sRBC%)detected by UF-1000i automatic urine analyzer for the identification of hematuria.Methods The 126 patients with hematuria admitted to Cancer Hospital of Putian City from July 2018 to June 2021 were selected as research subjects,including 61 cases with glomerulonephritis(GN)hematuria and 65 cases with non-glomerulonephritis(NGN).Urine samples from all patients were tested,dysmorphic red blood cell percentage(dRBC%)was examined by a microscope.UF-sRBC%was automatically analyzed using UF-1000i analyzer.Pearson correlation analysis was used to evaluate the correlation between dRBC%and UF-sRBC%.Area under receiver operator characteristic curve(AUC)was calculated to evaluate the diagnositic value of above indicators for GN hematuria.Results The dRBC%and UF-sRBC%levels in GN group were higher than those in NGN group[dRBC%:(33.4±24.5)%vs(3.1±2.8)%,UF-sRBC%:(35.8±28.9)%vs.(14.6±13.6)%,both P<0.05].Pearson correlation analysis demonstrated a positive correlation between dRBC%and UF-sRBC%(r=0.678,P<0.0001).The AUC of dRBC%and UF-sRBC%was 0.774 and 0.747,the sensitivity was 75.6%and 72.3%,the specificity was 75.4%and 76.7%,and the optimal cut-off values were 6.9%and 29.3%.Conclusions UF-sRBC%and dRBC%have similar diagnostic value for GN hematuria.UF-sRBC%is an automated parameter and is more convenient for initial screening and identification of GN.

关 键 词：肾小球肾炎性血尿 异形红细胞比例 小红细胞比例 

分 类 号：R446.12[医药卫生—诊断学] R692.31[医药卫生—临床医学] R696.8