过渡金属催化的内烯烃不对称硼氢化  

Transition Metal Catalyzed Asymmetric Hydroboration of Internal Alkenes

作　　者：陆候祥 李必杰 Lu Houxiang;Li Bijie(Center of Basic Molecular Science,Department of Chemistry,Tsinghua University,Beijing 100084)

机构地区：[1]清华大学化学系,基础分子科学中心,北京100084

出　　处：《有机化学》2022年第10期3167-3182,共16页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21971139)资助项目。

摘　　要：金属催化的烯烃不对称硼氢化是构建手性硼酸酯最为有效的方法之一,具有原料简单易得、原子经济性高、硼化产物结构多样等特点,受到化学家的广泛关注.总结了过渡金属催化的内烯烃的不对称硼氢化,包括张力环状内烯烃、苯乙烯类内烯烃及含配位基团的内烯烃.Transition metal catalyzed asymmetric hydroboration of alkenes is one of the most powerful methods to prepare chiral organoboronates, which has attracted extensive attention of chemists due to its simple raw materials, high atomic economy, diverse structure of borated products, etc. The transition metal catalyzed enantioselective hydroboration of internal alkenes including strained internal alkene, β-substituted styrenes and internal alkenes bearing a coordinating group is summarized.

关 键 词：硼氢化 不对称催化 内烯烃 硼酸酯 

分 类 号：O621.251[理学—有机化学]