内蒙古地区成人高尿酸血症和痛风流行病学特征及其危险因素分析  

Epidemiological characteristics and risk factors of hyperuricemia and gout in adults in Inner Mongolia

作　　者：赵文娟 刘丽君[2] 李向红 王平乐 贾平 王永福[1] ZHAO Wen-juan;LIU Li-jun;LI Xiang-hong;WANG Ping-le;JIA Ping;WANG Yong-fu(Department of Rheumatology,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia O14010,China;不详)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院风湿免疫科,内蒙古包头014010 [2]内蒙古通辽市医院肾病风湿科 [3]赤峰学院附属医院风湿免疫科 [4]内蒙古巴彦尔市医院风湿免疫科 [5]内蒙古乌兰察布市中心医院肾病风湿科

出　　处：《应用预防医学》2022年第5期421-425,431,共6页Applied Preventive Medicine

摘　　要：目的了解内蒙古地区成人高尿酸血症(HUA)和痛风患病率及HUA的危险因素,为其预防控制提供参考。方法在内蒙古包头市、通辽市、赤峰市、锡林浩特市、乌兰察布市和巴彦淖尔所属的6家医院选取2019年度体检的部分18岁以上当地居民进行问卷调查,收集社会人口学、疾病史、家族史、饮食生活方式等信息资料,并测量血压、身高、体重和检测甘油三酯、胆固醇、血糖、肌酐、尿酸等指标,分析高尿酸血症及痛风患病率及其危险因素。结果从2308名居民中检出HUA 364例,在2244名居民中发现痛风114例,患病率分别为15.8%和5.1%。根据第七次人口普查内蒙古自治区人口性别年龄构成进行标化后的HUA、痛风患病率分别为15.6%和5.0%。调查对象中HUA和痛风患病率均为男性高于女性,差异均有统计学意义(均为P<0.001);HUA患病率汉族高于蒙古族、城市高于农村,差异均有统计学意义(均为P<0.05)。患高血压、糖尿病、高脂血症、吸烟、饮酒、喜食肉食(>2次/周)、每次食肉量>50 g、不体育锻炼、存在HUA家族史及痛风家族史者HUA患病率相对较高,差异均有统计学意义(均为P<0.05)。多因素logistic回归分析发现男性、高血压、喜食肉食、不体育锻炼、有痛风家族史等均是高尿酸血症的危险因素(均为P<0.05),OR(95%CI)值分别为2.72(2.99-3.69)、1.55(1.14-2.11)、1.44(1.14-1.82)、0.70(0.55-0.90)和2.34(1.16-4.71)。结论内蒙古地区高尿酸血症和痛风患病率分别为15.6%和5.0%。男性、高血压、喜食肉食、不体育锻炼、有痛风家族史是高尿酸血症的独立危险因素。Objective To understand the prevalence and risk factors of hyperuricemia(HUA)and gout in adults in Inner Mongolia,and provide reference for the prevention and control.Methods A part of the local residents over the age of 18 who underwent physical examination in 2019 from six hospitals affiliated to Baotou city,Tongliao city,Chifeng city,Xilinhot city,Ulanqab city,and Bayan Nur city in Inner Mongolia were selected to conduct a questionnaire survey,and their socio-demographic,disease history,family history,dietary lifestyle and other information were collected;blood pressure,height,weight and triglyceride,cholesterol,blood sugar,creatinine,uric acid and other indicators were measured;the prevalence and risk factors of hyperuricemia and gout were analyzed.Results Among2308 residents,there were 364 cases of HUA detected,and 114 cases of gout in 2244 residents detected,with prevalence rates of 15.8%and 5.1%,respectively.After the gender and age standardization of the population in Inner Mongolia Autonomous Region in the seventh census,the prevalence of HUA and gout were 15.6%and 5.0%,respectively.The prevalence of HUA and gout in men were significantly higher than women(P<0.001).The prevalence rates of HUA in Han ethnicity was significantly higher than Mongolian ethnicity,and in urban areas were higher than rural areas,and the differences were statistically significant(all P<0.05).People with hypertension,diabetes,hyperlipidemia,smoking,drinking alcohol,meat preference(>2 times/week),eating meat>50 g each time,no physical exercise,having family history of HUA and gout had relatively higher prevalence of HUA,and the differences were statistically significant(all P<0.05).Multivariate logistic regression analysis showed that male,hypertension,meat preference,no physical exercise,and family history of gout were risk factors for hyperuricemia(all P<0.05),the OR(95%CI)were 2.72(2.99-3.69),1.55(1.14-2.11),1.44(1.14-1.82),0.7(0.55-0.90),and 2.34(1.16-4.71),respectively.Conclusion The prevalence of hyperuricemia and gout in In

关 键 词：高尿酸血症 痛风 患病率 高血压 

分 类 号：R195.4[医药卫生—卫生统计学]