右美托咪定与硬膜外阻滞复合全身麻醉对胸腔镜肺癌手术的临床效果分析  

Clinical Effect Analysis of Dexmedetomidine Combined with Epidural Block Combined with General Anesthesia on Thoracoscopic Lung Cancer Surgery

作　　者：张宏岩 岳海龙 马俊涛 侯国清 李俊杰 Zhang Hong-yan;Yue Hai-long;Ma Jun-tao;Hou Guo-qing;Li Jun-jie(Department of Thoracic Surgery,Tang Central Hospital,Tangshan 063000,Hebei Province,China;Department of Anesthesiology,Tang Central Hospital,Tangshan 063000,Hebei Province,China;Department of Emergency and Critical Care Medicine,Tang Central Hospital,Tangshan 063000,Hebei Province,China)

机构地区：[1]唐山中心医院胸外科,河北唐山063000 [2]唐山中心医院麻醉科,河北唐山063000 [3]唐山中心医院急诊重症医学科,河北唐山063000

出　　处：《中外医药研究》2022年第6期84-86,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:比较右美托咪定与硬膜外阻滞复合全身麻醉对胸腔镜肺癌手术的临床效果。方法:选取2020年12月-2021年12月唐山中心医院收治的胸腔镜肺癌手术患者150例为观察对象,随机数字表法分研究组1、研究组2、研究组3三组,各50例。研究组1行全身麻醉,研究组2行右美托咪定复合全身麻醉,研究组3行硬膜外阻滞复合全身麻醉。比较三组麻醉效果、手术指标、血流动力学指标。结果:研究组2总有效率高于研究组1,差异有统计学意义(P<0.05);研究组3总有效率高于研究组1,差异有统计学意义(P<0.05);研究组2、研究组3麻醉起效时间、手术时间短于研究组1,差异有统计学意义(P<0.05);研究组2与研究组3麻醉起效时间、手术时间比较,差异无统计学意义(P>0.05);T_(2)、T_(3)时,三组呼吸频率(RR)水平均降低、心率(HR)水平均升高,研究组2、研究组3 HR水平低于研究组1、RR水平高于研究组1,差异无统计学意义(P>0.05),研究组2与研究组3 HR、RR水平比较,差异无统计学意义(P>0.05)。结论:胸腔镜手术治疗肺癌患者采取右美托咪定或硬膜外阻滞复合全身麻醉,无较大区别,均具有较高临床价值,能够提高麻醉效果,稳定患者血流动力学指标。Objective:To compare the clinical effect of dexmedetomidine combined with epidural block combined with general anesthesia on thoracoscopic surgery for lung cancer.Methods:A total of 150 patients with thoracoscopic lung cancer surgery admitted to Tangshan Central Hospital from December 2020 to December 2021 were selected as the observation objects.They were divided into study group 1,study group 2 and study group 3 according to random digital number table method,with 50 cases in each group.The study group 1 was given general anesthesia,study group 2 was given dexmedetomidine combined with general anesthesia,and study group 3 was given epidural block combined with general anesthesia.The anesthetic effect,surgical index and hemodynamic index were compared among the three groups.Results:The total effective rate of study group 2 was higher than that of study group 1,and the difference was statistically significant(P<0.05).The total effective rate of study group 3 was higher than that of study group 1,and the difference was statistically significant(P<0.05).The anesthesia onset time and operation time of study group 2 and study group 3 were shorter than those of study group 1,and the difference was statistically significant(P<0.05).There was no significant difference in anesthesia onset time and operation time between study group 2 and study group 3(P>0.05).The respiratory rate(RR)levels at T_(2) and T_(3) in the three groups were reduced,and the heart rate(HR)levels were increased,and the HR levels of study group 2 and study group 3 were lower than those of study group 1 and RR levels were higher than those of study group 1,with no significant difference(P>0.05).There was no significant difference between study group 2 and study group 3 in HR and RR levels(P>0.05).Conclusion:Dexmedetomidine or epidural block combined with general anesthesia for thoracoscopic surgery for lung cancer patients have no significant difference,both therapies have high clinical value,can improve the effect of anesthesia and stabilize the hem

关 键 词：胸腔镜手术 肺癌 右美托咪定 硬膜外阻滞 全身麻醉 

分 类 号：R61[医药卫生—外科学]