某院2021年844例输液药品不良反应分析  

Analysis on 844 cases of adverse reactions of infusion drugs in our hospital in 2021

作　　者：张清泉[1] 章宝燕[1] 林志强[1] ZHANG Qingquan;ZHANG Baoyan;LIN Zhiqiang(Department of Pharmacy,Quanzhou First Hospital Affiliated to Fujian Medical University,Fujian,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属泉州第一医院药剂科,福建泉州362000

出　　处：《中国医药科学》2022年第22期108-111,共4页China Medicine And Pharmacy

摘　　要：目的分析福建医科大学附属泉州第一医院(我院)2021年844例输液药品不良反应发生的特点及规律,为临床合理用药制订高效的处理措施。方法对我院2021年从各个科室收集的并上报到国家药品不良反应(ADR)监测中心的844例输液ADR按患者的性别、年龄、引发ADR的药品种类、ADR涉及器官或系统及临床表现、ADR的转归及报告人职业进行回顾分析。结果844例ADR中>60岁患者所占比例最大(332例,占39.3%);引起ADR的主要药品种类为抗肿瘤药物(288例,占34.1%),其次为中枢神经系统药物(96例,占11.4%);ADR的血液系统损害为主要临床表现(216例,占25.6%);多数ADR经采取相应措施后好转或痊愈(822例,占97.4%);ADR上报人员以医生为主(840例,占99.6%)。结论加强ADR的监测,提高医务人员对ADR的认识和重视程度,促进临床合理用药,保障患者用药安全。Objective To analyze the characteristics and underlying rules of 844 cases of adverse reactions of infusion drugs in Quanzhou First Hospital Affiliated to Fujian Medical University(our hospital)in 2021,so as to formulate efficient treatment measures for clinical rational drug use.Methods A total of 844 infusion adverse drug reactions(ADR)collected from various departments in our hospital in 2021 and reported to the National Center for ADR Monitoring,China were retrospectively analyzed by the gender and age of the patients,the types of drugs causing ADR,the organs or systems involved in ADR and clinical manifestations,the outcome of ADR and the occupation of the reporting personnel.Results Among the 844 cases of ADR,patients over 60 years old accounted for the largest proportion(332 cases,39.3%).The main drugs causing ADR were antitumor drugs(288 cases,accounting for 34.1%),followed by central nervous system drugs(96 cases,accounting for 11.4%).Blood system damage due to ADR was the main clinical manifestation(216 cases,accounting for 25.6%).Most ADRs were improved or recovered after taking corresponding measures(822 cases,accounting for 97.4%).ADR reporting personnel were mainly doctors(840 cases,accounting for 99.6%).Conclusion It is necessary to strengthen the monitoring of ADR and improve the awareness and attention of medical staff to ADR,thus promoting clinical rational drug use and ensuring the safety of patients in terms of drug use.

关 键 词：药品不良反应 用药监测 输液药品 合理用药 

分 类 号：R95[医药卫生—药学]