呼吸道病原体检测平台应用进展  

Application progress of respiratory pathogen detection platform

作　　者：周承勃森 贾红(综述) 鞠长燕(审校)[2] ZHOU Chengbosen;JIA Hong;JU Changyan(School of Public Health,Southwest Medical University,Luzhou,Sichuan 646000,China;Nanshan District Center for Disease Control and Prevention,Shenzhen,Guangdong 518000,China)

机构地区：[1]西南医科大学公共卫生学院,四川泸州646000 [2]广东省深圳市南山区疾病预防控制中心,广东深圳518000

出　　处：《国际检验医学杂志》2022年第24期3057-3064,共8页International Journal of Laboratory Medicine

基　　金：深圳市“医疗卫生三名工程”引进高层次医学团队项目(SZSM201803081);深圳市南山区科技计划项目(南科研卫第2020006号);深圳市南山区医学重点学科项目(传染病预防与控制)。

摘　　要：呼吸道感染(RTIs)是临床感染性疾病的主要死因。随着医学技术的高速发展,呼吸道病原体检测技术取得了巨大进展,其中高通量测序技术平台在呼吸道罕见病原体诊断中发挥了重要作用。该文基于传统病原体检测技术、生物芯片技术以及二代测序技术,结合呼吸道病原体检测平台的应用,从技术原理、临床应用展开述评,以期为呼吸道病原体高通量检测的临床实践提供参考。Respiratory tract infections(RTIs)are the main cause of death in clinical infectious diseases.With the rapid development of medical technology,great progress has been made in respiratory pathogen detection technology.Among them,the platform of high-throughput sequence technology has played an important role in the diagnosis of rare respiratory pathogens.Based on the traditional pathogen detection technology,biochip technology and second-generation sequencing technology,combined with the application of respiratory pathogen detection platform,this paper reviews their technical principles and clinical applications in order to provide a reference for the clinical practice of respiratory pathogen detection.

关 键 词：呼吸道病原体 高通量检测 检测平台 综述文献 

分 类 号：R446[医药卫生—诊断学]