孕产期五色专案管理在梅毒感染孕产妇管理中的效果评价  

Effect Evaluation of Five-color Project Management in Pregnant Women with Syphilis Infection During Pregnancy and Perinatal Period

作　　者：覃黄娜[1] 唐丽春[1] 李慧 谢小花[1] 覃清华[1] 唐明英 黄美凤[1] 李冬如[1] QIN Huangna;TANG Lichun;LI Hui;XIE Xiaohua;QIN Qinghua;TANG Mingying;HUANG Meifeng;LI Dongru(Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning 530003,China)

机构地区：[1]广西壮族自治区妇幼保健院,南宁530003

出　　处：《中国艾滋病性病》2022年第11期1281-1284,共4页Chinese Journal of Aids & STD

基　　金：广西卫健委自筹课题(Z20210350)。

摘　　要：目的探讨高危五色专案管理在梅毒孕妇管理中的应用效果。方法通过全国“预防艾滋病、梅毒和乙肝母婴传播管理信息系统”,选取本院确诊并报告的,填报日期为2016年1月1日至2021年12月31日的梅毒感染且已分娩的孕妇为研究对象。将研究对象分为高危五色专案管理实施前和实施后两个组,比较孕期追踪随访用药治疗、妊娠结局和儿童随访情况。结果共纳入梅毒感染孕产妇251例,所生儿童256例。其中高危五色专案管理实施前组孕产妇100例,所生儿童102例;实施后组孕产妇151例,所生儿童154例。2016-2021年梅毒感染孕产妇治疗率呈逐年上升趋势,由2016年的57.1%上升至2021年的91.2%。实施前组梅毒孕产妇治疗率为62.0%(62/100)、实施后组孕产妇治疗率为90.7%(137/151);实施前组所生儿童预防性治疗率为61.8%(63/102),实施后组儿童预防性治疗率为75.3%(116/154),以上差异均有统计学意义。实施后组的儿童失访率为15.7%(19/121),远低于实施前组的86.3%(88/102),差异有统计学意义(χ2=110.437,P<0.001)。结论孕产期五色专案管理能够促进预防梅毒母婴传播工作,提高梅毒感染孕产妇治疗率及所生儿童预防性治疗率;提升儿童随访质量,减少儿童失访,尽早明确母婴阻断效果。Objective To explore the effectiveness of high-risk five-color special management in the management of pregnant syphilis women.Methods Pregnant women with syphilis infection who were diagnosed and reported in our hospital and had given birth from January 1,2016 to December 31,2021 were included,through the National Management Information System for Prevention of Mother-to-child Transmission of HIV,Syphilis and Hepatitis B.The subjects were divided into two groups,before and after the implementation of high-risk five-color special management,to compare the follow-up of medication treatment during pregnancy,pregnancy outcome and child follow-up.Results A total of 251pregnant women with syphilis infection and 256 children were included.Among them,there were 100 pregnant women and 102 children in the pre-implementation group of high-risk five-color special management.There were 151 pregnant women and 154 children in the post-implementation group.From 2016 to 2021,the treatment rate of syphilis infected pregnant women showed an annual upward trend,rising from 57.1%in 2016 to 91.2%in 2021.The treatment rate of syphilis was 62.0%(62/100)in the pre-implementation group and 90.7%(137/151)in the post-implementation group.The rate of preventive treatment for children was 61.8%(63/102)in the pre-implementation group and 75.3%(116/154)in the post-implementation group,and the difference was statistically significant.The lost follow-up rate of children in the post-implementation group was 15.7%(19/121),which was much lower than the 86.3%(88/102)in the pre-implementation group.Conclusions Five-color project management during pregnancy and perinatal period can promote the prevention of motherto-child transmission of syphilis and improve the treatment rate of syphilis infected pregnant women and children.To improve the quality of follow-up,reduce the loss of children to follow-up,and identify the effect of mother-tochild blocking as early as possible.

关 键 词：梅毒孕妇 五色专案管理 效果评价 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]