一起航班输入9例新型冠状病毒肺炎病例特点分析  

Analysis of 9 imported cases of COVID-19 by one aircraft

作　　者：郑靖[1] 陈平 蒋丽娜[1] 魏泽 张怡盾[1] 李莉[1] 陈泽辉[1] 陈鹏[6] 荣飚[1] 韩俊[2] Zheng Jing;Chen Ping;Jiang Lina;Wei Ze;Zhang Yidun;Li Li;Chen Zehui;Chen Peng;Rong Biao;Han Jun(Xiamen Center for Disease Control and Prevention,Xiamen 361021,China;State Key Laboratory of Infection Disease Prevention and Control,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Kaizhou District People’s Hospital,Chongqing 405400,China;The First Affiliated Hospital of Bengbu Medical College,Bengbu 233000;Baotou Medical School,College of Public Health,Baotou 014040,China;Branch of Xinglin,the First Affiliated Hospital of Xiamen University,Xiamen 361022,China)

机构地区：[1]厦门市疾病预防控制中心,厦门361021 [2]中国疾病预防控制中心病毒病预防控制所传染病预防控制国家重点实验室,北京102206 [3]开州区人民医院,重庆405400 [4]蚌埠医学院第一附属医院,蚌埠233030 [5]包头医学院公共卫生学院,包头014040 [6]厦门大学附属第一医院杏林分院,厦门361022

出　　处：《中华实验和临床病毒学杂志》2022年第5期547-551,共5页Chinese Journal of Experimental and Clinical Virology

基　　金：福建省卫生健康科技计划项目(2020CXB050)。

摘　　要：目的分析厦门市一起境外输入新型冠状病毒肺炎疫情及传播特点,为制定入境人员防控策略提供科学依据。方法采集11月19日俄罗斯航班入境人员鼻咽拭子及血清,检测新型冠状病毒核酸和相关抗体。对核酸检测阳性的病例和无症状感染者进行个案调查。4例进行全基因组核酸测序。根据核酸和抗体检出先后,以及病例在飞机上的座次分析其机舱内传播风险。结果同一架次飞机输入8例确诊病例和1例无症状感染者。9例病例均自俄罗斯乘机回国。2020年11月21日,3例核酸检测阳性;11月22日,4例核酸阳性;11月25日和26日,分别检出一例核酸阳性。3例获得全基因组序列,1例获得85%序列。根据流行病学、病毒基因组进化特点、核酸和抗体检测结果,以及病例座次存在聚集,飞机机舱内存在聚集传播风险。结论此为1起入境人员机舱内暴发疫情,存在机舱内传播风险。厦门市对境外输入人员采取全链条闭环管控,及时有效发现输入病例,遏制疫情传播扩散,为国内经飞机输入病例发现和处置提供了借鉴。Objective To analyze the transmissible characteristics of imported COVID-19 cases in Xiamen.Methods The nasopharyngeal swabs and serum specimens were collected from inbound passengers on the same flight.The nucleic acid and antibodies to SARS-CoV-2 were detected respectively.The type of COVID-19 was determined according to the condition.The mode of transmission was analyzed according to the incidence and laboratory diagnosis of positive cases,and seats of cases on the plane.Results Five cases of common type,3 cases of mild type and 1 case of asymptomatic infection were found in the same Russian flight.Three cases,5 cases,1 case and 1 case were detected for nucleic acid on November 21,22,25 and 26,2020.The whole genome sequence was obtained in 3 cases and 85%in 1 case.According to epidemiology,evolutionary characteristics of virus genome,Results of qPCR and antibody and case seating,the risk of transmission in aircraft cabin was analyzed.Conclusions This is COVID-19 cases reports of inbound personnel in aircraft,and there is a risk of transmission in the cabin.The imported cases were isolated timely and effectively with the whole closed-loop.No other cases of infection occurred.This report provides a reference for the detection and prevention of transmission of cases imported by aircraft.

关 键 词：新型冠状病毒肺炎 境外输入 传播路径 防控 

分 类 号：R563.1[医药卫生—呼吸系统]