唇龈沟入路和鼻内镜入路手术对上颌骨囊肿患者复发率、骨质再生良好率的影响  

Effect of labiogingival groove surgical approach and nasal endoscopic approach on recurrence rate and bone regeneration rate in patients with maxillary bone cyst

作　　者：王斌[1] 王健 胡晓东 江雪[1] 刘卫卫[1] WANG Bin;WANG Jian;HU Xiao-dong(Department of E.N.T.,Cangzhou Central Hospital,Cangzhou Hebei 061000,China.)

机构地区：[1]沧州市中心医院耳鼻喉科,河北沧州061000

出　　处：《临床和实验医学杂志》2022年第22期2445-2448,共4页Journal of Clinical and Experimental Medicine

基　　金：沧州市重点研发计划指导项目(编号:204106132);河北省2020年度医学科学研究课题(编号:202006854)。

摘　　要：目的研究唇龈沟入路和鼻内镜入路手术对上颌骨囊肿患者复发率、骨质再生良好率的影响。方法回顾性选取2019年6月至2021年6月沧州市中心医院收治的78例上颌骨囊肿患者作为研究对象,根据不同手术方式分为研究组(39例)和常规组(39例),常规组选用唇龈沟入路术治疗,研究组选用鼻内镜入路手术治疗。比较两组手术相关指标(手术时间、术中出血量、伤口愈合时间);比较两组治疗前后炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-6、IL-8]和疼痛程度(VAS)评分;比较两组患者复发率、骨质再生良好率。结果研究组患者手术时间、术中出血量和伤口愈合时间为(24.78±2.11)min、(34.72±3.18)mL、(3.64±0.19)d,均显著低于常规组[(42.36±2.36)min、(52.44±3.63)mL、(5.77±0.22)d],差异均有统计学意义(P<0.05)。治疗后,两组患者血清TNF-α、IL-6和IL-8水平均显著降低,且研究组TNF-α、IL-6和IL-8水平为(15.31±1.19)、(16.23±1.29)、(13.95±1.33)ng/L,显著低于常规组[(19.33±2.12)、(20.16±1.77)、(15.87±1.21)ng/L],差异均有统计学意义(P<0.05)。治疗后,两组患者VAS评分均显著降低,且研究组VAS评分为(2.32±0.26)分,显著低于常规组[(3.49±0.31)分],差异均有统计学意义(P<0.05)。研究组患者复发率为2.56%,显著低于常规组(15.38%);研究组患者骨质再生良好率为94.87%,显著高于常规组(79.48%),差异均有统计学意义(P<0.05)。结论对于上颌骨囊肿患者,鼻内镜入路手术效果明显高于唇龈沟入路术,复发率和骨质再生良好率均明显更佳。Objective To study the effect of labiogingival groove surgical approach and nasal endoscopic approach on recurrence rate and bone regeneration rate in patients with maxillary bone cyst.Methods Seventy-eight patients with maxillary bone cysts in Cangzhou Central Hospital from June 2019 to June 2021 were retrospectively selected,and classified into two groups according to different surgical approaches,each with 39 cases.Routine group received labiogingival groove surgical approach,while study group received nasal endoscopic approach.Then comparison was conducted on operation indexes(hospital stay length,intraoperative blood loss,wound healing time),inflammation factors[tumour necrosis factor-α(TNF-α),interleukin(IL)-6,IL-8],visual analogue scale(VAS)score,recurrence rate and good rate of bone regeneration.Results The operation time,intraoperative blood loss and wound healing time of the patients in the study group were(24.78±2.11)min,(34.72±3.18)mL,(3.64±0.19)d,which were significantly lower than those in the routine group[(42.36±2.36)min,(52.44±3.63)mL,(5.77±0.22)d],the differences were statistically significant(P<0.05).After treatment,the serum levels of TNF-α,IL-6 and IL-8 in the two groups were significantly decreased,and the levels of TNF-α,IL-6 and IL-8 in the study group were(15.31±1.19),(16.23±1.29),(13.95±1.33)ng/L,which were significantly lower than those in the conventional group[(19.33±2.12),(20.16±1.77),(15.87±1.21)ng/L],the difference was statistically significant(P<0.05).After treatment,the VAS scores of the two groups were significantly decreased,and the VAS scores of the study group were(2.32±0.26)points,which were significantly lower than those of the routine group[(3.49±0.31)points],and the differences were statistically significant(P<0.05).The recurrence rate of the patients in the study group was 2.56%,which was significantly lower than that in the conventional group(15.38%).The good rate of bone regeneration in the study group was 94.87%,which was significantly higher than th

关 键 词：唇龈沟入路 鼻内镜入路 上颌骨囊肿 复发率 骨质再生良好率 

分 类 号：R765.9[医药卫生—耳鼻咽喉科]