高龄冠心病患者PCI术后发生MACE的影响因素  

Influencing factors of MACE after PCI in advanced aged patients with coronary heart disease

作　　者：史玛诺 冯珊珊[1] 于源[1] SHI Ma-nuo;FENG Shan-shan;YU Yuan(Department of Cardiology,Beijing Jishuitan Hospital,Beijing,100000,China)

机构地区：[1]北京积水潭医院心内科,北京昌平100000

出　　处：《心血管康复医学杂志》2022年第6期688-692,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究高龄冠心病患者经皮冠状动脉介入治疗(PCI)后发生主要不良心血管事件(MACE)的影响因素。方法:依据是否发生MACE,于我院行PCI术的248例高龄冠心病患者被分为MACE组(46例)与无MACE组(202例)。比较两组一般临床资料,并分析高龄冠心病患者PCI术后发生MACE的影响因素。结果:与无MACE组比较,MACE组年龄>80岁,合并高血压、糖尿病、高血脂、吸烟,植入支架数量≥3枚、平均血小板体积(MPV)≥11.2fl、血清高敏C反应蛋白(hsCRP)水平≥0.5mg/L、血清尿酸水平≥360μmol/L比例均显著升高(P均<0.01)。多因素Logistic回归分析显示,年龄>80岁、高血压、糖尿病、高血脂、吸烟、植入支架数量≥3枚、MPV≥11.2fl、血清hsCRP水平≥0.5mg/L、血清尿酸水平≥360μmol/L是高龄冠心病患者PCI术后发生MACE的独立危险因素(OR=2.373~4.199,P<0.05或<0.01)。结论:年龄、高血压等指标为高龄冠心病患者PCI术后发生MACE的独立危险因素,临床上应当密切关注此类患者的这些指标,提早进行干预。Objective:To study influencing factors of major adverse cardiovascular events(MACE)after percutaneous coronary intervention(PCI)in advanced aged patients with coronary heart disease(CHD).Methods:According to MACE or not,a total of 248 advanced aged CHD patients undergoing PCI in our hospital were divided into MACE group(n=46)and no MACE group(n=202).General clinical data were compared between two group,and influencing factors of MACE after PCI in these patients were analyzed.Results:Compared with no MACE group,there were significant rise in percentages of age>80 years old,hypertension,diabetes mellitus(DM),hyperlipidemia,smoking,number of implanted stents≥3,mean platelet volume(MPV)≥11.2fl;serum level of high sensitivity C-reactive protein(hsCRP)≥0.5mg/L and serum uric acid(SUA)level≥360μmol/L in MACE group(P<0.01 all).Multivariate Logistic regression analysis indicated that age>80 years old,hypertension,DM,hyperlipidemia,smoking,number of implanted stents≥3,MPV≥11.2fl,serum hsCRP level≥0.5mg/L and SUA level≥360μmol/L were independent risk factors for MACE after PCI in advanced aged CHD patients(OR=2.373~4.199,P<0.05 or<0.01).Conclusion:Age,hypertension etc.are independent risk factors for MACE after PCI in advanced aged CHD patients.Close attention should paid to these indexes in these patients in clinic in order to intervene early.

关 键 词：冠心病 血管成形术 气囊 冠状动脉 危险因素 

分 类 号：R541.409[医药卫生—心血管疾病]