人工耳蜗植入后听觉皮层活动与听觉能力相关性研究  

Correlation between Auditory Cortex Activity and Hearing Ability after Cochlear Implantation

作　　者：辛甜宇 王宇洋 魏朝刚[1] 刘玉和[1] XIN Tianyu;WANG Yuyang;WEI Chaogang;LIU Yuhe(Department of Otolaryngology Head and Neck Surgery,Peking University First Hospital;Department of Otolaryngology Head and Neck Surgery,Hunan Provincial People's Hospital)

机构地区：[1]北京大学第一医院耳鼻咽喉头颈外科,北京100034 [2]湖南省人民医院耳鼻咽喉头颈外科,长沙410021

出　　处：《中华耳科学杂志》2022年第6期948-953,共6页Chinese Journal of Otology

基　　金：“北京市科学技术委员会”资助课题(Z191100006619027);国家自然科学基金面上项目资助课题(82071070);首都卫生发展科研专项(首发2022-1-2023);湖南省自然科学基金(2022JJ40225)联合资助。

摘　　要：目的探究听障儿童人工耳蜗植入后听觉皮层神经活动与听觉言语能力之间的联系。方法19例CI儿童开机后半年的队列研究,使用近红外光学成像及听觉言语量表评分,采用SPSS 25.0软件行相关性分析。结果情绪韵律引起的CI儿童的右侧颞区前部的激活程度与言语感知能力显著负相关,引起的右侧颞区后部及左侧颞区激活程度与言语感知能力显著正相关。结论人工耳蜗植入后早期,情绪语音韵律可能抑制右侧颞区前部神经反应,促进右侧颞区后部及左侧颞区神经反应增强,并与听觉言语功能的更好发展相关。Objective To investigate the association between neural activity in the auditory cortex and auditoryspeech ability in children after cochlear implantation.Methods A cohort study was conducted on 19 pediatric CI recipients.Neural activity in the auditory cortex and auditory-speech ability were gauged using fNIRS and behavioral scales,and the SPSS 25.0 software was used for correlation analysis.Results Activation of right anterior temporal cortex elicited by emotional prosody was negatively correlated with behavioral scores,while activation of right posterior temporal region and left temporal region was positively correlated with behavioral scores.Conclusion In the early stage after cochlear implantation,emotional prosody may inhibit the neural response in the right anterior temporal cortex,and promote the enhancement of the neural response in the right posterior temporal cortex and left temporal cortex.This may correlate to the better development of auditory speech ability.

关 键 词：人工耳蜗植入儿童 听觉皮层神经活动 

分 类 号：R764[医药卫生—耳鼻咽喉科]