肾综合征出血热患者窦性心动过缓与血碳酸氢根离子浓度的关联性  

Correlation between sinus bradycardia and blood bicarbonate ion in patients with hemorrhagic fever with renal syndrome

作　　者：李元 李吉镇 陈汉文 徐璐[2] 王娜[2] 董国霞[2] 刘雷[2] LI Yuan;LI Jizhen;CHEN Hanwen;XU Lu;WANG Na;DONG Guoxia;LIU Lei(School of Clinical Medicine,Jining Medical University,Jining 272013,China;Afiliated Hospital of Jining Medical University,Jining 272029,China)

机构地区：[1]济宁医学院临床医学院,济宁272013 [2]济宁医学院附属医院,济宁272029

出　　处：《济宁医学院学报》2022年第6期424-426,430,共4页Journal of Jining Medical University

基　　金：济宁医学院附属医院博士科研基金(2020-BS-014)。

摘　　要：目的探讨肾综合征出血热患者窦性心动过缓与血碳酸氢根离子浓度的相关性。方法选取2014年1月-2018年12月济宁医学院附属医院收治的肾综合征出血热患者153例为研究对象,分为观察组(并发窦性心动过缓,38例)和对照组(未并发窦性心动过缓,115例),收集临床资料,采集血样标本,分析肾综合征出血热患者血碳酸氢根离子浓度与窦性心动过缓的关联性。结果24.6%的肾综合征出血热患者发生了窦性心动过缓。两组患者血碳酸氧根离子浓度、尿蛋白水平、血小板计数、体温差异具有统计学意义(P<0.05),血碳酸氢根离子浓度在19.8~22mmol/L时,血碳酸氢根离子浓度每增加1mmol/L,肾综合征出血热患者窦性心动过缓风险增加60%(OR=1.6,95%CI 1.2~2.1,P<0.05)。结论肾综合征出血热患者的窦性心动过缓与血碳酸氢根离子浓度存在关联性。Objective To investigate the correlation between sinus bradycardia and blood bicarbonate ions in patients with renal syndrome hemorrhagic fever.Methods 154 patients with renal syndrome hemorrhagic fever admitted to the Affiliated Hospital of Jining Medical University between January 2014 and December 2018 were selected as the study subjects and divided into observation group(with concomitant sinus bradycardia,38 cases)and control group(without concomitant sinus bradycardia,115 cases).Clinical data such as patients'basic information,hospitalization days,hospital expenses,laboratory indexes,and heart rate at admission were collected to analyze the correlation between blood bicarbonate ion concentration and sinus bradycardia.Results Sinus bradycardia occurred in 24.6%of patients with renal syndrome hemorrhagic fever.The difference in blood bicarbonate ion concentration,urine protein level,platelet count,and body temperature between the two groups was statistically significant(P<0.05),and the risk of sinus bradycardia in patients with renal syndrome hemorrhagic fever increased by 60%for each 1 mmol/L increase in blood bicarbonate ion between 19.8 and 22 mmol/L(OR=1.6,95%CI 1.2~2.1,P<0.05).Conclusion There is an association between sinus bradycardia and blood bicarbonate in patients with renal syndrome hemorrhagic fever.

关 键 词：肾综合征出血热 窦性心动过缓 血碳酸氢根离子 

分 类 号：R512.8[医药卫生—内科学]