不同灸法配合针刺治疗成人变应性鼻炎随机对照试验的Meta分析  

Meta-analysis on Randomized Controlled Trials of Different Moxibustion Combined with Acupuncture in the Treatment of Adult Allergic Rhinitis

作　　者：张萍萍 费静雯 杨超[2] 于金娜[1] 孙少馨 彭唯娜[1] 王小溪[1] ZHANG Pingping;FEI Jingwen;YANG Chao;YU Jinna;SUN Shaoxin;PENG Weina;WANG Xiaoxi(Department of Acupuncture and Moxibustion,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)

机构地区：[1]中国中医科学院广安门医院针灸科,北京100053 [2]北京中医药大学东直门医院针灸科,北京100700

出　　处：《光明中医》2022年第19期3476-3481,共6页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：国家重点研发计划资助(No.2019YFC1712200)。

摘　　要：目的基于Meta分析系统评价不同灸法配合针刺治疗变应性鼻炎的有效性与安全性。方法计算机检索中国知网(CNKI)、中国生物医学文献服务系统(Sino Med)、万方数据知识服务平台(Wan Fang)、维普全文期刊数据库(VIP)、Pubmed、EMbase6个数据库,对纳入文献进行资料提取和质量评价后,采用Rev Man 5.3软件进行Meta分析。结果纳入11篇RCT文献,共1238例患者。Meta分析结果显示:不同灸法配合针刺治疗变应性鼻炎的综合评价优于西药组(OR=2.57,95%CI:1.69 to 3.91,P=0.34);温针灸改善变应性鼻炎的症状体征评分优于西药组(SMD=-0.30,95%CI:-0.53 to-0.06,P=0.88);温针灸改善变应性鼻炎的血清Ig E水平优于西药组(SMD=-1.32,95%CI:-1.55 to-1.10,P=0.43)。结论不同灸法配合针刺治疗变应性鼻炎安全有效,且优于西药,或可作为西药治疗变应性鼻炎的补充治疗,不会增加其不良反应。本系统评价结论仍需更多高质量、大样本、多中心的随机对照试验来提供进一步证据。Objective To systematically evaluate the efficacy and safety of different moxibustion combined with acupuncture in the treatment of allergic rhinitis based on Meta-analysis.Methods Seven databases including CNKI,sinomed,Wanfang,VIP,Pub Med,EMBASE and Cochrane library were searched by computer.After data extraction and quality evaluation of the included documents,Revman 5.3 software was used for meta-analysis.Results Eleven RCTs involving 1238 patients were included.The comprehensive evaluation of different moxibustion methods combined with acupuncture in the treatment of allergic rhinitis was better than that of western medicine group(OR=2.57,95%CI:1.69 to 3.91,P=0.34).The score of symptoms and signs improved by warm acupuncture was better than western medicine group(SMD=-0.30,95%CI:-0.53 to-0.06,P=0.88).The serum Ig E level of warm acupuncture was better than that of western medicine group in improving allergic rhinitis(SMD=-1.32,95%CI:-1.55 to-1.10,P=0.43).Conclusion Different moxibustion combined with acupuncture is safe and effective in the treatment of allergic rhinitis,which is superior to western medicine.Maybe it can be used as a supplementary treatment of Western medicine in the treatment of allergic rhinitis,without increasing its adverse reactions.However,more high-quality,large sample,multicenter randomized controlled trials are needed to provide further evidence for the conclusion of this systematic review.

关 键 词：变应性鼻炎 灸法 针刺疗法 META分析 

分 类 号：R246.81[医药卫生—针灸推拿学]