从肠道菌群角度探讨多囊卵巢综合征发病机制  

Study on the Pathogenesis of Polycystic Ovary Syndrome from the Point of View of Intestinal Flora

作　　者：孙洁[1] 刘静君(指导)[1] SUN Jie;LIU Jingjun(Shandong University of Traditional Chinese Medicine,Shandong Province,Jinan 250000,China)

机构地区：[1]山东中医药大学

出　　处：《光明中医》2022年第22期4060-4063,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：多囊卵巢综合征是一种病因复杂的内分泌及代谢紊乱性疾病,目前发病机制尚未完全明确。多囊卵巢综合征的发病主要与遗传和环境因素、胰岛素抵抗、高雄激素血症等相关。近年来肠道菌群失调作为目前多囊卵巢综合征研究中的热门新领域,研究发现通过微生物-肠-脑综合轴、代谢综合征、高雄激素血症、胰岛素抵抗等方式对机体产生影响。Polycystic ovary syndrome(PCOS)is an endocrine and metabolic disorder with complex etiology.At present,the pathogenesis of PCOS is not completely clear,which is mainly related to genetic and environmental factors,insulin resistance,hyperandrogenemia and so on.In recent years,intestinal flora imbalance is a hot new field in PCOS research.It has been found that intestinal flora imbalance affects the body through microbial-enteric-brain axis,metabolic syndrome,hyperandrogenemia,insulin resistance and so on.

关 键 词：多囊卵巢综合征 病机 肠道菌群 脑-肠轴 

分 类 号：R711.75[医药卫生—妇产科学]