经腹壁推压配合阴道B超探头调整卵巢位置在取卵术中的应用  

Application of transabdominal wall press and vaginal B-ultrasound probe to adjust ovarian position in oocyte retrieval

作　　者：邹湘丽 许丽燕[1] 邹嫦娥[1] Zou Xiangli;Xu Liyan;Zou Chang′e(Center for Reproductive Medicine,Peking University Shenzhen hospital,Shenzhen 518002,China)

机构地区：[1]北京大学深圳医院生殖医学中心,深圳518002

出　　处：《中国医师杂志》2022年第11期1606-1609,共4页Journal of Chinese Physician

基　　金：国家重点研发项目(2018YFC1002104)。

摘　　要：目的探讨经腹推压调整卵巢位置对取卵困难患者的疗效和安全性。方法采用回顾性病例对照研究, 收集2020年1月至2021年12月北京大学深圳医院生殖医学中心取卵困难的患者共177例, 76例患者采用经腹推压法调整卵巢位置取卵(推压组), 另外101例患者常规取卵(对照组)。比较两种取卵方法的获卵率、获卵数、成熟卵数、可移植胚胎数和优质胚胎数, 记录并发症的发生率。结果两组卵巢刺激方案、促排药剂量、人绒毛膜促性腺激素(HCG)日≥14 mm卵泡数比较差异均无统计学意义(均P>0.05)。推压组的促排时间长于对照组, HCG日雌二醇水平显著高于对照组(均P<0.05)。推压组获卵率、获卵数、成熟卵数、可移植胚胎数和优质胚胎数均显著高于对照组(均P<0.05)。推压组取卵手术并发症的发生率明显低于对照组(P=0.003)。结论对于取卵困难的患者, 经腹推压调整卵巢位置可以提高取卵率, 减少并发症的发生。Objective The aim of this study was to investigate the efficacy and safety of rtansabdominal wall press to adjust ovarian position in patients with difficulty in oocyte retrieval.Methods A retrospective case-control study was conducted to collect 177 patients with difficulty in oocyte retrieval from January 2020 to December 2021 in the Reproductive Medical Center of Peking University Shenzhen Hospital.Among the 177 patients with difficulty in oocyte retrieval,76 patients used transabdominal wall press to adjust the position of the ovary(pushing group),and the other 101 patients were treated with routine oocyte retrieval(control group).The oocyte retrieval rate,the number of oocyte and mature oocyte,the number of transferable embryos and high-quality embryos were compared between the two groups,and the incidence of complications was recorded.Results There was no significant difference between the two groups in the ovarian stimulation program,the dosage of ovulation promoting drugs and the number of follicles≥14 mm on human chorionic gonadotropin(HCG)day(all P>0.05).The days of promoting ovulation in the pushing group were longer than those in the control group,and the level of estradiol on HCG day was significantly higher than that in the control group(all P<0.05).The rate of oocyte retrieval,the number of oocytes retrieved,the number of transferable embryos and high-quality embryos in the pushing group were significantly higher than those in the control group(all P<0.05).The incidence of complications during oocyte retrieval in the pushing group was significantly lower than that in the control group(P=0.003).Conclusions Transabdominal wall press to adjust ovarian position can improve oocyte retrieval rate and reduce the incidence of complications in patients with difficulty in oocyte retrieval.

关 键 词：卵母细胞抽取 超声检查 卵巢位置 排卵诱导 

分 类 号：R714.8[医药卫生—妇产科学]