经典名方枇杷清肺饮的研究进展  

Advance in study on compound Pipa Qingfei Decoction

作　　者：李宇琦 胡泽萍 张福明 鄂秀辉 秦民坚[1] 何毅 LI Yuqi;HU Zeping;ZHANG Fuming;E Xiuhui;Qin Minjian;HE Yi(School of Pharmacy,China Pharmaceutical University,Nanjing 211198,China;Development Center of Modern Chinese Medicine,Tasly Pharmaceutical Group Co.Ltd.,Tianjin 300410,China;State Key Laboratory of Critical Technology in Innovative Chinese Medicine,Tasly Pharmaceutical Group Co.Ltd.,Tianjin 300410,China)

机构地区：[1]中国药科大学中药学院,南京211198 [2]天士力医药集团股份有限公司研究院现代中药开发中心,天津300410 [3]天士力医药集团股份有限公司创新中药关键技术国家重点实验室,天津300410

出　　处：《天津中医药大学学报》2022年第6期797-805,共9页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：国家“重大新药创制”科技重大专项(2017ZX09301005)。

摘　　要：枇杷清肺饮源自清代《外科大成·卷三》,由枇杷叶,桑白皮,黄连,黄柏,人参,甘草6味药材组成,全方具有清肺泄热,和胃下气的功效,是用于治疗肺经风热证痤疮类皮肤疾病的名家药方,被收录于国家中医药管理局2018年发布的《古代经典名方目录(第一批)》中,现代研究表明,枇杷清肺饮具有明显的抗炎,抗菌,抗病毒,增强免疫等药理作用,在临床治疗痤疮、酒渣鼻、脂溢性皮炎等方面表现出较好的疗效。通过查阅文献,本文从处方出处、组方分析、主治病症、化学成分、临床应用概况等方面对枇杷清肺饮进行总结与分析,以期为经典名方枇杷清肺饮的进一步研究开发提供参考依据。Pipa Qingfei Decoction was contained in the Great Achievements of Surgery:Volume Ⅲ in the Qing dynasty. It was composed of six medicinal materials of Eriobotryae Folium,Cortex Mori,Coptis Chinensis,Cortex Phellodendri,Ginseng,and Licorice. It is a famous classical formula for treating acne-like skin diseases. It is included in the Classic Catalogue of Ancient Classics:First Batch issued by the State Administration of Traditional Chinese Medicine in 2018. Modern Studies have shown that Pipa Qingfei Decoction has the obvious comprehensive activities of antiviral,anti-inflammatory,antibacterial,and immune-enhancing,and has shown good curative effects in the clinical treatment of acne,rosacea,and seborrheic dermatitis. According to the literatures on the study of Pipa Qingfei Decoction published in recent years,this paper summarizes and analyzes the historical evolution,compatibility analysis,prescription analysis,chemistry constituents,and clinical application,which can provide a reference for the research and development of the Pipa Qingfei Decoction.

关 键 词：枇杷清肺饮 历史沿革 临床应用 化学成分 

分 类 号：R289.3[医药卫生—方剂学]