剪切波弹性成像及平面波超敏感血流显像技术在糖尿病肾病评估中的应用价值  

Application value of shear wave elastography and angio planewave ultrasensitive imaging in the assessment of diabetic nephropathy

作　　者：时俊雨 王春光[2] 刘禹彤 张帅[1] 宋晓 SHI Junyu;WANG Chunguang;LIU Yutong;ZHANG Shuai;SONG Xiao(School of Medical Imaging,Weifang Medical University,Weifang 261053,China;Department of Ultrasound,Weifang People’s Hospital,Weifang 261041,China)

机构地区：[1]潍坊医学院医学影像学院,山东潍坊261053 [2]山东省潍坊市人民医院超声科,山东潍坊261041

出　　处：《医学影像学杂志》2022年第12期2104-2107,共4页Journal of Medical Imaging

摘　　要：目的探讨剪切波弹性成像(SWE)及平面波超敏感血流显像(Angio PLUS)技术在糖尿病肾病(DN)评估中的应用价值。方法选取在我院就诊的DN患者125例为DN组,根据尿蛋白/肌酐(ACR)水平不同将其分为DNⅠ~Ⅲ组,DNⅠ组:正常白蛋白尿组(ACR<30 mg/g),DNⅡ组:微量白蛋白尿组(30 mg/g≤ACR≤300 mg/g),DNⅢ组:大量白蛋白尿组(ACR>300 mg/g);另选取同期44例健康志愿者作为对照组。采用SWE及Angio PLUS技术分别测量右肾中部肾实质杨氏模量均值(Emean)及右肾近被膜肾皮质小叶间动脉血流阻力指数(RI),比较各组间Emean及RI值的变化。结果与对照组相比,DNⅠ~Ⅲ组杨氏模量均值以及小叶间动脉血流阻力指数均升高(P<0.05);且随着ACR值增加,DNⅠ~Ⅲ组肾实质杨氏模量均值及小叶间动脉血流阻力指数逐渐升高,各组间比较差异均有统计学意义(P<0.05)。结论SWE及Angio PLUS技术均可无创评估DN的严重程度,具有重要的临床意义。Objective To investigate the application value of shear-wave elastography(SWE)and angio planewave ultrasen sitive imaging(Angio PLUS)in assessing diabetic nephropathy(DN).Methods A total of 125 diabetic nephropathy patients treated at our hospital were divided into three groupⅠ~Ⅲaccording to the different levels of urinary albumin/creatinine ratio(ACR),i.e.,GroupⅠ:normoalbuminuria group(ACR<30 mg/g),Group II:microalbuminuria group(30 mg/g≤ACR≤300 mg/g),group III:macroalbuminuria group(ACR>300 mg/g),and 44 healthy volunteers were selected as the control group.The SWE and Angio PLUS were used to measure the parenchyma Young's modulus(Emean)of the middle of right kidney and the RI of interlobular artery of the right kidney cortical area near the renal capsule,the changes of Young's modulus and RI were compared among the four groups.Results Compared with healthy control group,young's modulus and RI of interlobular artery in DNⅠ~Ⅲgroups were increased(P<0.05).With the increase of ACR,young's modulus of renal parenchymal and RI of interlobular artery increased gradually,and there were statistically significant differences among all groups(P<0.05).Conclusion SWE and Angio PLUS can noninvasively evaluate the severity of diabetic nephropathy,which has important clinical significance.

关 键 词：糖尿病肾病 剪切波弹性成像 平面波超敏感血流显像 超声检查 

分 类 号：R587.2[医药卫生—内分泌] R445.1[医药卫生—内科学]