经皮神经电刺激联合药物对慢性前列腺炎/慢性盆腔疼痛综合征的疗效  

Efficacy of transcutaneous electrical nerve stimulation combined with drugs in the treatment of chronic prostatitis/chronic pelvic pain syndrome

作　　者：陆军 张磊[1] 张学学 高明 孟平 魏迪 敦鑫龙 尚仕浩 袁建林[1] LU Jun;ZHANG Lei;ZHANG Xuexue;GAO Ming;MENG Ping;WEI Di;DUN Xinlong;SHANG Shihao;YUAN Jianlin(Department of Urology,Xijing Hospital,Air Force Military Medical University,Xi'an 710032;Department of Urology,Xi'an Daxing Hospital,Xi'an 710002;The Cadet Team 6 of School of Basic Medicine,Air Force military Medical University,Xi'an 710032,China)

机构地区：[1]中国人民解放军空军军医大学西京医院泌尿外科,陕西西安710032 [2]西安大兴医院泌尿外科,陕西西安710002 [3]中国人民解放军空军军医大学基础医学院学员六大队,陕西西安710032

出　　处：《现代泌尿外科杂志》2022年第12期1004-1008,共5页Journal of Modern Urology

基　　金：国家自然科学基金项目(No.61971425);西京医院学科助推计划项目(No.XJZT18D05);西北地区电生理适宜技术应用于男科疾病诊治真实世界研究(No.HDSL202001081);电生物适宜技术在男科疾病防治中的应用(No.HDSL202001080)。

摘　　要：目的观察经皮神经电刺激(TENS)对慢性前列腺炎/慢性盆腔疼痛综合征(CP/CPPS)的临床疗效。方法选取空军军医大学第一附属医院泌尿外科就诊的CP/CPPS患者140例,随机分为治疗组和对照组,治疗组采用经皮神经电刺激联合药物治疗,对照组采取药物治疗,观察比较治疗前后两组患者慢性前列腺炎症状评分(NIH-CPSI)、国际前列腺症状评分(IPSS)、治疗有效率等指标的变化。结果共122例患者完成了整个临床研究。治疗后,两组患者NIH-CPSI评分和IPSS评分较治疗前均显著降低(P<0.001),且两组患者间NIH-CPSI评分和IPSS评分有统计学差异(P<0.001)。治疗组总体有效率(95.1%)高于对照组(90.2%),且治疗组显效率(70.5%)明显高于对照组(4.9%),差异均有统计学意义(P<0.001)。与对照组相比,治疗组NIH-CPSI评分变化值(分)与年龄(岁)具有较强的正相关关系(r=0.477,P<0.001)。结论与单一药物治疗相比,TENS联合药物可明显改善CP/CPPS患者的临床症状,其治疗显效率明显高于单一药物治疗;与中青年患者相比,TENS疗法可能更适合中老年患者。Objective To observe the clinical efficacy of transcutaneous electrical nerve stimulation(TENS)in the treatment of chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS).Methods A total of 140 CP/CPPS patients treated in the Department of Urology of Xijing Hospital were selected and randomly divided into the treatment group and control group.The treatment group received TENS combined with drug therapy,and the control group received drug therapy only.Changes in chronic prostatitis symptom index(NIH-CPSI),international prostate score symptom(IPSS),treatment response rate and other indicators were compared between the two groups before and after treatment.Results A total of 122 patients completed the entire clinical study.After treatment,the NIH-CPSI and IPSS scores of the two groups were significantly lower than those before treatment(P<0.001),and there were significant differences between the two groups(P<0.001).The overall effective rate(95.1%)of the treatment group was higher than that of the control group(90.2%),and the markedly effective rate(70.5%)of the treatment group was significantly higher than that of the control group(4.9%),with a statistically significant difference(P<0.001).The NIH-CPSI score change(points)in the treatment group had a strong positive correlation with age(years)(r=0.477,P<0.001).Conclusion Compared with single drug treatment,TENS combined with drugs can significantly improve the clinical symptoms of CP/CPPS patients,and its efficacy is significantly higher than that of single drug treatment.TENS therapy may be more suitable for elderly patients than for young and middle-aged patients.

关 键 词：慢性前列腺炎/慢性盆腔疼痛综合征 经皮神经电刺激 药物治疗 慢性前列腺炎症状评分 国际前列腺症状评分 

分 类 号：R697.3[医药卫生—泌尿科学]