电感耦合等离子体质谱法测定地龙药材中铅、砷、汞、镉、铜元素的残留量  

Determination of Pb,As,Hg,Cd,Cu in Pheretima by Inductively Coupled Plasma Mass Spectrometry

作　　者：马彧[1] 李正刚 曲涵婷 赵艳 王路宏[1] MA Yu;LI Zheng-gang;QU Han-ting;ZHAO Yan;WANG Lu-hong(Siping Institute for Food and Drug Control,Siping 136000,Jilin China;Jilin Institutes for Drug Control,Changchun 130000,China;Siping Social Psychiatric Hospital,Siping 136001,Jilin China)

机构地区：[1]四平市食品药品检验所,吉林四平136000 [2]吉林省药品检验研究院,吉林长春130000 [3]四平市社会精神病院,吉林四平136001

出　　处：《分析测试技术与仪器》2022年第4期427-432,共6页Analysis and Testing Technology and Instruments

基　　金：吉林省中药材标准及中药饮片炮制规范(项目编号:JLPZGF-2020-052)。

摘　　要：建立电感耦合等离子体质谱法(ICP-MS)测定不同产地和批次地龙药材中铅(Pb)、砷(As)、汞(Hg)、镉(Cd)、铜(Cu)5种重金属元素的含量.采用微波消解进行样品前处理,结果表明:5种重金属元素的线性关系良好(r≥0.999 6),平均回收率在92.8%~95.2%范围内,方法的检出限在0.001 0~0.092 mg/kg范围内.方法灵敏度高,重复性好,方法准确.不同产地和批次的样品中5种重金属元素均有检出.地龙药材中Pb、As、Hg、Cd、Cu这5种重金属元素需要重点监控.An Inductively coupled plasma mass spectrometry(ICP-MS)method has been set up to determine the contents of five heavy metal elements,namely lead(Pb),arsenic(As),mercury(Hg),cadmium(Cd)and copper(Cu),in different habitats and batches of Pheretima.The sample was pretreated by microwave digestion.The results showed that the linearity of the five heavy metal elements were good(r≥0.9996),the average recoveries were in the range of 92.8%~95.2%,and the detection limits of the method were in the range of 0.0010~0.092 mg/kg.The detection method is of highly sensitive,repeatable and accurate.Five heavy metal elements were detected in samples from different habitats and batches.These five heavy metal elements of Pb,As,Hg,Cd and Cu in Pheretima need to be monitored with emphasis.

关 键 词：微波消解 电感耦合等离子体质谱 地龙 重金属元素 

分 类 号：O657.63[理学—分析化学]