超声随访BI-RADS 3类结节声像图特征变化在其良恶性鉴别诊断中的价值  

Value of ultrasonographic follow-up of BI-RADS 3 nodules in the differential diagnosis of benign and malignant nodules

作　　者：陈惠婷 杨丹南 黄立嘉 CHEN Huiting;YANG Dannan;HUANG Lijia(Department of Ultrasound,Huizhou Central People’s Hospital,Guangdong 516001,China)

机构地区：[1]广东省惠州市中心人民医院超声科,516001

出　　处：《临床超声医学杂志》2022年第12期911-914,共4页Journal of Clinical Ultrasound in Medicine

基　　金：惠州市科技计划项目(0024206150424021)。

摘　　要：目的 应用超声随访乳腺影像报告和数据系统(BI-RADS)3类结节的声像图特征变化,探讨其在良恶性鉴别诊断中的应用价值。方法 选取于我院行超声随访的115例BI-RADS 3类结节患者,分析其随访期间结节声像图特征的变化,比较良恶性结节最大径增长率、前后径增长率、走行变化、形态变化、边界变化、内部回声变化及钙化变化。应用多因素Logistic回归分析BI-RADS 3类结节声像图特征变化的影响因素;绘制受试者工作特征(ROC)曲线分析声像图特征变化鉴别诊断BI-RADS 3类良恶性结节的效能。结果 115例患者随访结束证实良性91例,恶性24例。良恶性结节最大径增长率、前后径增长率、边界及内部回声比较差异均有统计学意义(均P<0.05),其余声像图特征变化比较差异均无统计学意义。多因素Logistic回归分析显示,最大径增长率、前后径增长率及边界变化均为BI-RADS 3类结节恶性化的影响因素(OR=1.575、1.640、1.732,均P<0.05);ROC曲线分析显示,最大径增长率、前后径增长率及边界变化鉴别诊断BI-RADS 3类良恶性结节的曲线下面积分别为0.635、0.820、0.598,3项特征联合应用的曲线下面积为0.868。结论 超声随访BI-RADS 3类结节的声像图特征变化对其良恶性鉴别诊断具有一定价值,可为临床诊断提供参考。Objective To investigate the ultrasonographic feature changes of breast imaging reporting and data system(BI-RADS)3 nodules,and to explore the application value in the differential diagnosis of benign and malignant nodules.Methods A total of 115 patients with BI-RADS 3 nodules underwent ultrasonic follow-up no our hospital were selected.The ultrasonographic feature changes of BI-RADS 3 nodules during the follow-up period were analyzed. The maximum diameter growth rate,anteroposterior diameter growth rate,course change,shape change,boundary change,internal echo change and calcification change of benign and malignant nodules were compared.Multivariate Logistic regression analysis was performed to analyze the influencing factors of ultrasonographic features changes of BI-RADS 3 nodules. Receiver operating characteristic(ROC)curve was drawn to analyze the efficacy of ultrasonographic feature changes in the differential diagnosis of benign and malignant nodules.Results Among the 115 patients,91 patients were benign and 24 patients were malignant. There were statistically signifiant differences in maximum diameter growth rate,anteroposterior diameter growth rate,boundary change,internal echo change between benign and malignant nodules(all P<0.05).There were no significant differences in the changes of other ultrasonographic features between benign and malignant nodules.Multivariate Logistic regression analysis showed that the maximum diameter growth rate,anteroposterior diameter growth rate,and boundary change were influencing factors for the deterioration of malignant BI-RADS 3 nodules(OR=1.575,1.640,1.732,all P<0.05).ROC curve analysis showed that the area under the curve of the maximum diameter growth rate,anteroposterior diameter growth rate,and boundary change in the differential diagnosis of benign and malignant BI-RADS 3 nodules were 0.635,0.820 and 0.598,respectively.The area under the curve of combination of the three was 0.868.Conclusion Ultrasonographic follow-up of BI-RADS 3 nodules has certain value in the

关 键 词：超声检查 乳腺影像报告和数据系统 乳腺结节 3类 良恶性 随访 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]