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作 者:李湘平 邓春华[1] LI Xiang-ping;DENG Chun-hua(Department of Urology and Andrology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China)
机构地区:[1]中山大学附属第一医院泌尿外科,广东广州510080
出 处:《中山大学学报(医学科学版)》2022年第6期871-877,共7页Journal of Sun Yat-Sen University:Medical Sciences
基 金:国家自然科学基金(82101819,81971314,82171604,81971759)。
摘 要:随着婚育年龄推迟,大龄夫妇生育需求逐渐增加,生殖衰老成为社会发展面临的重要公共卫生问题。研究表明40~55岁可能为男性生育力的“分水岭”。然而,相比女性生殖衰老,男性生殖衰老特征缺乏鲜明特征,对机体的复杂影响表现为多方面。本篇综述中,我们从男性生殖内分泌、生殖腺,以及生殖附属性腺的衰老性变化角度,阐述对男性生殖衰老特征的认识。With the postponement of marriage and childbirth age and the opening of the"three child"policy,the reproductive demand of advanced ages is increasing,and reproductive aging has become an important public health issue facing social development.Previous studies have shown that 40~55 years old may be the"watershed"of male fertility during aging.However,compared with female reproductive aging,male reproductive aging lacks distinctive characteristics,and its impact on the elderly men is multifaceted.In this review,we elaborated our understanding of the male reproductive aging from multiple perspectives of aging-related changes in male reproductive endocrine,gonads,and accessory sex glands.
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