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作 者:黄燕平[1] 刘炜[1] 张明[1] 徐士冉 张涛[1] 卢慕峻[1] HUANG Yan-ping;LIU Wei;ZHANG Ming;XU Shi-ran;ZHANG Tao;LU Mu-jun(Department of Urology and Andrology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200001,China)
机构地区:[1]上海交通大学医学院附属仁济医院泌尿男科,上海200001
出 处:《中山大学学报(医学科学版)》2022年第6期892-897,共6页Journal of Sun Yat-Sen University:Medical Sciences
基 金:仁济医院临床研究“五新”及培养项目(PYIII20-05)。
摘 要:【目的】分析男科门诊早泄(PE)患者的临床特征及影响因素。【方法】收集2020年1月至2022年5月医院男科门诊20~60岁男性患者,详细记录一般人口学资料、病史、性生活史等,对符合要求的患者行早泄诊断量表(PEDT)、自我评估阴道内射精潜伏期(IELT)、国际勃起功能问卷-5(IIEF-5)、勃起硬度评分(EHS)、广泛性焦虑障碍量表(GAD-7)和健康问卷抑郁量表等量表评估。采用多元线性回归及Logistic回归分析PE的相关因素及独立危险因子。【结果】共纳入男科门诊患者973例,其中PE组445例(31.12±6.72)岁,非PE组528例(32.78±7.95)岁。两组间年龄、PEDT、IELT、IIEF-5、EHS、GAD-7及PHQ-9的差异均存在统计学意义(P<0.05)。回归分析校正后,PEDT与年龄(b=-0.11,P=0.001)、IIEF-5(b=-0.17,P<0.001)及PHQ-9(b=0.19,P<0.001)存在显著相关性。多因素校正后,年龄≤30岁、勃起功能障碍及抑郁状态三个变量有统计学意义(P<0.01),其OR(95%CI)值分别为1.63(1.23,2.16)、2.05(1.45,2.92)、1.90(1.37,2.65)。【结论】PE与年龄、勃起功能评分、焦虑及抑郁评分等因素密切相关。年龄≤30岁、勃起功能障碍及抑郁状态是PE的独立危险因子。【Objective】To analyze the clinical characteristics and influencing factors of premature ejaculation(PE)in andrology outpatient population.【Methods】From January 2020 to May 2022,a total of 973 male subjects aged 20-60 years were enrolled in the andrology outpatient department of our hospital,and the subjects’demographic data,medical history and sexual history were recorded in detail.Subjects with complete data were further evaluated by the Premature Ejaculation Diagnostic Tool(PEDT),self-estimated intra-vaginal ejaculation latency time(IELT),International Index of Erectile Function 5(IIEF-5),Erectile Hardness Score(EHS),General Anxiety Disorder-7(GAD-7)and Patients Health Questionnaire-9(PHQ-9).Among the subjects,445 cases(31.12±6.72 years old)were assigned to the PE group and 528 cases(32.78±7.95 years old)to the non-PE group based on their medical and sexual histories,and results of the evaluation.Multiple linear regression and Logistic regression were used to analyze the correlation factors and independent risk factors of PE.【Results】There were significant differences in the indicators including age,PEDT,IELT,IIEF-5,EHS,GAD-7 and PHQ-9 between the two groups(P<0.05).Linear regression analysis showed that PEDT was significant-ly correlated with age(adjusted b=-0.11,P=0.001),IIEF-5(adjusted b=-0.17,P<0.001)and PHQ-9(adjusted b=0.19,P<0.001).After multivariate adjustment of Logistic regression,the variables such as age≤30 years,erectile dys-function and depression status were the independent risk factors for PE,and their Odds Ratio(OR)(95%CI)were 1.63(1.23,2.16),2.05(1.45,2.92)and 1.90(1.37,2.65),respectively.【Conclusions】PE significantly correlates with age,erectile function scale scores,anxiety and depression scale scores.Age≤30 years,erectile dysfunction and depression sta-tus are the independent risk factors for PE.
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