某三甲医院门诊微生态制剂处方用药分析  

Medication Analysis of Microecological Agent Prescriptions in the Outpatient Department of a Tertiary-Level Hospital

作　　者：裴婕 康怡 王子惠[1] PEI Jie;KANG Yi;WANG Zihui(Department of Pharmacy,Beijing Chao—Yang Hospital,Capital Medical University,Beijing,China 100020)

机构地区：[1]首都医科大学附属北京朝阳医院药事部,北京100020

出　　处：《中国药业》2022年第24期115-117,共3页China Pharmaceuticals

摘　　要：目的 提高门诊微生态制剂处方的规范性及合理性。方法 调取某三甲医院门诊2020年1月1日至2021年12月31日所有含微生态制剂的处方,对其用法用量、适应证等进行专项点评,分析用药合理性。结果 共纳入有效处方52 879张,涉及患者34 909例次,年龄集中于21-40岁(42.65%),女性(53.25%)稍多于男性(46.75%);使用科室主要集中在消化内科(37 015张,70.00%)和急诊科(6 620张,12.52%);单次剂量、频次不合理处方分别有73张,419张,除重后共计491张(0.93%);无适应证处方1 622张(3.07%),其中急诊科无适应证处方集中于使用地衣芽孢杆菌活菌胶囊(92.14%,211/229),儿科集中于使用枯草杆菌二联活菌颗粒(85.59%,101/118),但其中用于治疗肠易激综合征、幽门螺杆菌感染、恶性肿瘤等已有相应指南支持。结论 该院门诊微生态制剂近2年的临床使用基本合理,应持续进行其用法用量和适应证的管理,并随时关注相应指南的更新,进一步促进合理用药。Objective To improve the standardization and rationality of microecological agent prescriptions in the outpatient department.Methods All the prescriptions containing microecological agents from January 1,2020 to December 31,2021 in the outpatient department of a tertiary-level hospital were collected,and their usage,dosage,and indications were specifically reviewed to analyze the rationality of medication.Results A total of 52 879 effective prescriptions with 34 909 patients were involved,the patient′s age was mainly from 21 to 40 years old(42. 65%),and the proportion of female(53. 25%) was slightly higher than that of male(46. 75%). The departments using microecological agents were mainly the Department of Gastroenterology(37 015prescriptions,70. 00%) and the Department of Emergency(6 620 prescriptions,12. 52%). There were 73 prescriptions with unreasonable single dose and 419 prescriptions with unreasonable frequency,and 491 prescriptions(0. 93%) were obtained after weight removal. There were 1 622 prescriptions without indications(3. 07%),of which the Department of Emergency mainly used Live Bacillus Licheniformis Capsules(92. 14%,211/229),and the Department of Pediatrics mainly used Live Bacillus Subtilis Particles(85. 59%,101/118),but there were corresponding guidelines for the treatment of irritable bowel syndrome,Helicobacter pylori infection,malignant tumors,etc.Conclusion The clinical use of microecological agents in the outpatient department of the hospital in the past two years is reasonable. It is necessary to continue the management of the usage,dosage and indications of microecological agents,and pay attention to the updating of the corresponding guidelines at any time to further promote rational drug use.

关 键 词：微生态制剂 三甲医院 处方点评 合理用药 

分 类 号：R969.3[医药卫生—药理学]