人脱细胞羊膜在生物医学领域中的应用研究进展  

Research progress in application of human acellular amniotic membrane in biomedical field

作　　者：许发亚 何琪 李细艳 涂皎 肖雁冰 XU Faya;HE Qi;LI Xiyan;TU Jiao;XIAO Yanbing(Department of Gynecology and Obstetrics,Maternal and Child Health Care HospitalAffiliated to Zunyi Medical University,Zunyi,Guizhou,563000)

机构地区：[1]遵义医科大学附属妇幼保健院妇产科,贵州遵义563000

出　　处：《实用临床医药杂志》2022年第22期123-127,共5页Journal of Clinical Medicine in Practice

基　　金：国家自然科学基金资助项目(81460233);贵州省遵义市科学技术局-遵义妇幼保健院联合科技研发资金项目[遵市科合社字(2018)210号]。

摘　　要：人脱细胞羊膜(HAAM)是经过物理、化学或生物酶制剂将人新鲜羊膜进行脱细胞处理后得到的一种天然支架材料,其具有良好的生物相容性、低免疫原性、三维立体空间结构及取材方便等优点,在软组织修复、气管及尿道重建、皮肤伤口愈合、骨缺损修复、预防粘连等方面具有广泛的应用前景。本研究结合相关文献对HAAM支架在生物医学领域的应用研究进展进行综述。Human acellular amniotic membrane(HAAM)is a natural scaffold material obtained after the acellular treatment of fresh human amniotic membrane with physical,chemical or biological enzymes,which is featured as good biocompatibility,low immunogenicity,three-dimensional solid space structure and convenient material extraction,and has broad application prospects in soft tissue repair,trachea and urethra reconstruction,skin wound healing,bone defect repair and adhesion prevention.This study aimed to review the application of HAAM stent in biomedical field.

关 键 词：人脱细胞羊膜 生物工程 生物支架 组织修复 组织重建 

分 类 号：R318[医药卫生—生物医学工程] Q819[医药卫生—基础医学]