输尿管硬镜联合软镜钬激光碎石术治疗复杂性输尿管上段结石患者的效果  

Effect of Rigid Ureteroscope Combined with Soft Ureteroscope Holmium Laser Lithotripsy in the Treatment of Patients with Complicated Upper Ureteral Calculi

作　　者：郑涛 ZHENG Tao(Tongshan District Hospital of Traditional Chinese Medicine in Xuzhou City,Xuzhou 221116,China)

机构地区：[1]徐州市铜山区中医院,江苏徐州221116

出　　处：《中外医学研究》2022年第34期145-149,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析输尿管硬镜联合软镜钬激光碎石术治疗复杂性输尿管上段结石患者的临床效果。方法:收集2018年1月-2021年6月徐州市铜山区中医院收治的118例复杂性输尿管上段结石患者,根据电脑数字表法随机分为两组,各59例。对照组予以输尿管硬镜钬激光碎石术,观察组予以输尿管硬镜联合软镜钬激光碎石术。比较两组的围手术期指标、临床疗效、炎症指标与复发情况。结果:观察组的手术操作时间长于对照组,但术中失血量少于对照组,同时肠鸣音恢复、术后排便及住院时间均短于对照组(P<0.05)。观察组的治疗有效率是96.61%,高于对照组的84.75%(P<0.05)。术后3 d,观察组的血清肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞介素-6(IL-6)及降钙素原(PCT)水平均低于对照组(P<0.05)。术后1个月、半年及1年时给予患者复查,观察组的复发率均低于对照组(P<0.05)。结论:输尿管硬镜联合软镜钬激光碎石术治疗复杂性输尿管上段结石患者,不仅能改善围手术期指标,提高手术效果,而且还能改善炎症指标,预防复发。Objective:To analyze the clinical effect of rigid ureteroscope combined with soft ureteroscope holmium laser lithotripsy in patients with complicated upper ureteral calculi.Method:A total of 118 cases of patients with complicated upper ureteral calculi were admitted to Tongshan District Hospital of Traditional Chinese Medicine in Xuzhou City from January 2018 to June 2021 were collected.According to the method of computer numerical table,they were randomly divided into two groups,59 cases in each group.The control group was treated with rigid ureteroscope holmium laser lithotripsy,the observation group was treated with rigid ureteroscope combined with soft ureteroscope holmium laser lithotripsy.The perioperative indicators,clinical efficacy,inflammatory indicators and recurrence were compared between the two groups.Result:The operation time in the observation group was longer than that in the control group,but the intraoperative blood loss was less than that in the control group,and the recovery time of bowel sounds,postoperative defecation time and hospitalization time were all shorter than those in the control group(P<0.05).The treatment effective rate in the observation group was 96.61%,which was higher than 84.75%in the control group(P<0.05).Three days after operation,the serum tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6)and procalcitonin(PCT)in the observation group were lower than those in the control group(P<0.05).One month,half a year and one year after operation,the recurrence rate in the observation group were lower than those in the control group(P<0.05).Conclusion:Rigid ureteroscopy combined with soft ureteroscope holmium laser lithotripsy in patients with complicated upper ureteral calculi can not only improve perioperative indicators and surgical results,but also improve inflammatory indicators and prevent recurrence.

关 键 词：复杂性输尿管上段结石 输尿管硬镜联合软镜钬激光碎石术 临床疗效 炎症指标 复发 

分 类 号：R699.4[医药卫生—泌尿科学]