2018—2020年福建省出生缺陷儿治疗性引产情况  

Therapeutic induction of labor in infants with birth defects in Fujian Province from 2018 to 2020

作　　者：齐元杰 林英英 朱文斌[2] QI Yuanjie;LIN Yingying;ZHU Wenbin(Department of Obstetrics and Gynecology,Fujian Maternity and Child Health Hospital,Fujian Province,Fuzhou 350001,China;Department of Healthcare,Fujian Maternity and Child Health Hospital,Fujian Province,Fuzhou 350001,China)

机构地区：[1]福建省妇幼保健院妇产科,福建福州350001 [2]福建省妇幼保健院保健部,福建福州350001

出　　处：《中国当代医药》2022年第35期152-155,159,共5页China Modern Medicine

摘　　要：目的分析2018—2020年福建省出生缺陷儿治疗性引产情况,以探讨干预措施。方法收集2018—2020年福建省出生缺陷监测体系内103所医院的围生儿临床资料,对治疗性引产个案进行统计分析。结果2018—2020年共监测围生儿795475例,出生缺陷儿31475例,出生缺陷儿行治疗性引产8188例,占26.01%。诊断依据以超声和染色体检查结果异常为主,占比分别为71.31%和20.57%。不同产妇年龄、常住地、文化程度、家庭收入、孕次、产次、孕龄、胎儿性别和胎数的出生缺陷儿治疗性引产占比比较,差异有统计学意义(P<0.05)。治疗性引产的主要原因为先天性心脏病、总唇裂、唐氏综合征、神经管畸形和脑积水。结论加强产前筛查和产前诊断,及早发现并及时进行治疗性引产,是减少出生缺陷发生和降低围生儿死亡率的关键。Objective To analyze the therapeutic induced labor in infants with birth defects in Fujian Province from 2018 to 2020 to explore intervention measures.Methods Clinical data of perinatal infants from 103 hospitals in the birth defect monitoring system of Fujian Province from 2018 to 2020 were collected,and therapeutic labor induction cases were statistically analyzed.Results From 2018 to 2020,795475 perinatal infants were monitored,31475 cases were born with birth defects,8188 cases were treated with therapeutic induction of labor,accounting for 26.01%.Ultrasonography and chromosomal abnormalities were the main diagnostic basis,accounting for 71.31%and 20.57%,respectively.There were statistically significant differences in the proportion of therapeutic induction of birth defects among different maternal age,residence,education level,family income,gestational number,number of births,gestational age,fetal sex and number of births(P<0.05).The main causes of therapeutic induced labor were congenital heart disease,total cleft lip,Down syndrome,neural tube malformations and hydrocephalus.Conclusion Strengthening prenatal screening and prenatal diagnosis,early detection and timely therapeutic induced labor are the keys to reducing the incidence of birth defects and reducing perinatal mortality.

关 键 词：出生缺陷 治疗性引产 产前筛查 三级预防 超声 

分 类 号：R179[医药卫生—妇幼卫生保健]