陈志刚教授基于脑髓-神-气体系治疗快速眼动睡眠行为障碍的经验撷要  

Experience summary of Professor Chen Zhigang in the treatment of rapid eye movement sleep behavior disorder based on the brain’s marrow-spirit-qi system

作　　者：李茜 陈志刚[2] 张昶[3] 任珊[2] LI Xi;CHEN Zhigang;ZHANG Chang;REN Shan(The Second Clinical Medical College,Beijing University of Chinese Medicine,Beijing100029,China;the First Department of Encephalopathy,Dongfang Hospital of Beijing University of Chinese Medicine,Beijing100078,China;Department of Traditional Chinese Medicine,Aerospace Center Hospital,Beijing100049,China)

机构地区：[1]北京中医药大学第二临床医学院,北京100029 [2]北京中医药大学东方医院脑病一科,北京100078 [3]航天中心医院中医科,北京100049

出　　处：《中国医药导报》2022年第33期124-127,133,共5页China Medical Herald

基　　金：国家中医药管理局“十一五”重点专科专病基金项目(040104001003);北京中医药大学基本科研业务费青年教师项目(2019-JYB-JS-125)。

摘　　要：快速眼动睡眠行为障碍(RBD)是以快速眼动(REM)期发生的肌肉迟缓丧失及异常行为为特征的疾病,主要表现为REM期肌肉失迟缓,出现与生动梦境相关的异常肢体活动。西医治疗方法主要包括氯硝西泮和褪黑素,但其治疗作用有限。中医方面对于本病的认识尚不明确,陈志刚教授结合临床经验,认为本病发病与肾相关,当从脑髓-神-气体系探讨核心病机。其中脑髓是基础结构,脑气是维持脑功能活动的物质之一,脑神是脑功能的外在体现,脑髓损伤,脑气不足,则神乱梦魇。本文基于脑髓-神-气体系,探讨本病中医病机,为中医药诊疗提供思路和参考。Rapid eye movement sleep behavior disorder(RBD) is a disease characterized by the loss of muscle atonia and abnormal behaviors occurring during rapid eye movement(REM). It is mainly manifested as muscle atonia during REM and abnormal body movements associated with vivid dreams. Western medicine treatment mainly includes Clonazepam and Melatonin, but its therapeutic effect is limited. The understanding of this disease in traditional Chinese medicine is still unclear. Professor Chen Zhigang, combining clinical experience, believes that the disease is related to kidney, and the core pathogenesis should be explored from the brain’s marrow-spirit-qi system. Brain’s marrow is the basic structure,while brain’s qi is one of the substances to maintain brain functional activities and brain’s spirit is the external manifestation of brain function. Brain’s marrow injury cause brain’s qi deficiency, then mind disorders and nightmare happens. Based on the brain’s marrow-spirit-qi system, this paper discusses the pathogenesis of the disease in traditional Chinese medicine,and provides ideas and reference for the diagnosis and treatment of Chinese medicine.

关 键 词：快动眼睡眠行为障碍 脑神 脑髓 脑气 中医 

分 类 号：R338.63[医药卫生—人体生理学]