生物反馈电刺激联合前列舒通胶囊治疗Ⅲ型前列腺炎的疗效及对血液流变学的影响  

Effect of biofeedback electric stimulation combined with Qianlie shutong capsule on type Ⅲ prostatitis and its influence on hemorheology

作　　者：王一哲 杨晓亮[1] 吴畏[1] 席俊华[1] 杨振兴 徐忠乐 齐伟[1] 张艳斌[1] WANG Yi-zhe;YANG Xiao-liang;WU Wei;XI Jun-hua;YANG Zhen-xing;XU Zhong-le;QI Wei;ZHANG Yan-bin(Department of Urology,the Second People's Hospital of Hefei,Hefei Hospital Affiliated to Anhui Medical University,Hefei 230011,Anhui,China)

机构地区：[1]安徽医科大学附属合肥医院·合肥市第二人民医院泌尿外科,安徽合肥230011

出　　处：《川北医学院学报》2022年第12期1609-1613,共5页Journal of North Sichuan Medical College

基　　金：安徽省合肥市卫生健康委应用医学研究项目(Hwk2020zd0011)。

摘　　要：目的:探讨前列舒通胶囊联合生物反馈电刺激治疗Ⅲ型前列腺炎的疗效。方法:选取150例确诊Ⅲ型前列腺炎患者,根据治疗方法不同分为对照组与观察组,每组各75例。对照组予以前列舒通胶囊治疗,观察组予以前列舒通胶囊联合生物反馈电刺激治疗,两组均连续治疗8周。比较两组临床疗效,于治疗前和治疗后行美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)、国际勃起功能障碍指数5项(IIEF-5)、早泄诊断工具量表(PEDT)、视觉模拟评分(VAS)、卡式生活质量(KPS)评分的测评,并行前列腺液肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、IL-1β水平和血液流变学指标的测定。结果:观察组治疗总有效率为93.06%,高于对照组的76.71%(P<0.05)。治疗后,观察组NIH-CPSI、PEDT、VAS评分均低于对照组(P<0.05);IIEF-5和KPS评分均高于对照组(P<0.05);观察组前列腺液TNF-α、IL-6、IL-1β水平均低于对照组(P<0.05);观察组血液高切、中切及低切黏度均低于对照组(P<0.05)。结论:前列舒通胶囊联合生物反馈电刺激比单用前列舒通胶囊治疗Ⅲ型前列腺炎,更能够促进前列腺炎症消退,改善血液流变学,缓解临床症状,提高生活质量。Objective:To investigate the curative effect of Qianlie shutong capsule combined with biofeedback electric stimulation in the treatment of type Ⅲ prostatitis.Methods:150 patients with type Ⅲ prostatitis were divided into control group and observation group according to different treatment methods, 75 cases in each group.The control group was treated with Qianlie shutong capsule, and the observation group was treated with qianlie shutong capsule combined with biofeedback electric stimulation.Both groups were treated for 8 weeks.The clinical efficacy was compared between the two groups.The National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI),5 items of International Index of Eerectile Function(IIEF-5),Premature Ejaculation Diagnostic Tool(PEDT),Visual Analogue Scale(VAS) and Karnofsky Performance Status(KPS) scores were evaluated before and after treatment.The levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),IL-1β in prostatic fluid and hemorheology indexes were measured.Results:The total effective rate of the observation group was 93.06 %,which was significantly higher than 76.71 % of the control group(P<0.05).After treatment, NIH-CPSI,PEDT and VAS scores in the observation group were lower than those in the control group(P<0.05),and IIEF-5 and KPS scores were higher than those in the control group(P<0.05).After treatment, the levels of TNF-α,IL-6 and IL-1β in the prostatic fluid of the observation group were lower than those of the control group(P<0.05).After treatment, the high shear, middle shear and low shear viscosity of blood in the observation group were lower than those in the control group(P<0.05).Conclusion:Qianlie shutong capsule combined with biofeedback electric stimulation in the treatment of patients with type Ⅲ prostatitis can promote the regression of prostate inflammation, improve hemorheology, alleviate clinical symptoms and improve quality of life.

关 键 词：前列腺炎 生物反馈电刺激 前列舒通胶囊 炎症 血液流变学 

分 类 号：R697[医药卫生—泌尿科学]