内镜下黏膜切除术与内镜下高频电切术治疗胃肠道无蒂息肉的临床对比研究  

Clinical comparative study of endoscopic mucosal resection and endoscopic high-frequency resection in the treatment of gastrointestinal sessile polyps

作　　者：颜雪方 杨熹 Yan Xuefang;Yang Xi(Department of Gastroenterology,Jiangsu Shengze Hospital,Suzhou,Jiangsu 215228,China)

机构地区：[1]江苏盛泽医院消化内科,江苏苏州215228

出　　处：《现代医学与健康研究电子杂志》2022年第23期62-65,共4页Modern Medicine and Health Research

摘　　要：目的探究与分析内镜下黏膜切除术与内镜下高频电切术治疗胃肠道无蒂息肉的效果。方法回顾性分析2019年2月至2022年2月江苏盛泽医院收治的胃肠道无蒂息肉患者104例,按照不同的手术治疗方法分为黏膜切除术组(54例)与高频电切术组(50例),对比两组息肉完整切除率、围术期指标、手术前后胃蛋白酶原及C反应蛋白的水平变化,同时观察治疗期间不良反应。结果黏膜切除术组与高频电切术组相比息肉完整切除率较高、术中出血率均较低、手术后开始进流食时间较短,差异有统计学意义(P<0.05)。两组手术时间、住院时间相比,差异无统计学意义(P>0.05)。两组术后与术前相比胃蛋白酶原Ⅰ及胃蛋白酶原Ⅱ水平均较高,C反应蛋白水平较高,但黏膜切除术组术后与高频电切术术后相比胃蛋白酶原Ⅰ及胃蛋白酶原Ⅱ水平均较高,C反应蛋白水平较低,差异有统计学意义(P<0.05)。两组患者不良反应发生率相比,差异无统计学意义(P>0.05)。结论内镜下黏膜切除术治疗胃肠道无蒂息肉与内镜下高频电切术相比具有较高的息肉完整切除率,围术期指标表现较好,有效修复了胃黏膜的情况,升高胃蛋白酶原的水平,炎症反应较低,且治疗期间不会增加不良反应发生率,安全性较高。Objective To explore and analyze the effect of endoscopic mucosal resection and endoscopic high-frequency resection in the treatment of gastrointestinal sessile polyps.Methods A retrospective analysis of 104 patients with gastrointestinal sessile polyps admitted to the Jiangsu Shengze Hospital from February 2019 to February 2022 were divided into mucosal resection group(n=54)and high-frequency electrical resection group(n=50)according to different surgical treatment methods.The polyp complete resection rate,perioperative indicators,levels of pepsinogen and C-reactive protein before and after surgery were compared between the two groups,and adverse reactions during treatment were observed.Results Compared with the high-frequency electrosurgery group,the mucosal resection group had a higher rate of complete polyp resection,lower intraoperative bleeding rate,and shorter time to start liquid food after surgery,and the differences were statistically significant(P<0.05).There was no significant difference in operation time and hospitalization time between the two groups(P>0.05).The levels of pepsinogen I and pepsinogenⅡand C-reactive protein were higher in the two groups after surgery than before surgery,but the levels of pepsinogen in the mucosal resection group after surgery were higher than those after high-frequency resection.The levels of I and pepsinogenⅡwere higher,and the level of C-reactive protein was lower,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Compared with endoscopic high-frequency resection,endoscopic mucosal resection in the treatment of gastrointestinal sessile polyps has a higher complete polyp resection rate and better perioperative indicators,effectively repairing the gastric mucosa and increasing the level of pepsinogen,and the inflammatory response is reduced,and the incidence of excessive adverse reactions will not increase during treatment,and the safety is hig

关 键 词：内镜下黏膜切除术 高频电切术 胃肠道无蒂息肉 胃蛋白酶原 C反应蛋白 

分 类 号：R656.9[医药卫生—外科学]