超声斑点技术结合血清心肌标志物对酒精性心脏病的诊断价值探讨  

Discussion of the Diagnostic Value of Ultrasound Speckle Technique Combined with Serum Myocardial Markers for Alcoholic Heart Disease

作　　者：袁莉芳 沈沙 陈惠珍 YUAN Lifang;SHEN Sha;CHEN Huizhen(Shenzhen Mental Health Center,Guangdong Province,Shenzhen 518020,China;不详)

机构地区：[1]广东省深圳市精神卫生中心(广东省深圳市康宁医院),广东深圳518020

出　　处：《中国医学创新》2022年第36期138-142,共5页Medical Innovation of China

基　　金：广东省高水平临床重点专科(深圳市配套建设经费)资助项目(SZGSP013)。

摘　　要：目的:探讨超声斑点技术结合血清心肌标志物对酒精性心脏病的诊断价值。方法:选取2019年3月-2022年9月深圳市精神卫生中心长期大量饮酒的112例患者,均接受常规超声检查、超声斑点技术、血清心肌标志物检查,分析超声斑点技术结合血清心肌标志物对酒精性心脏病的诊断效能。结果:112例患者检出酒精性心脏病45例,占比40.18%;阳性组左房内径(LAD)、舒张晚期最大血流速度(A)、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)值均高于阴性组,二尖瓣口舒张早期最大血流速度(E)、二尖瓣口舒张早期最大血流速度/舒张晚期最大血流速度(E/A)、每搏输出量(SV)、左室射血分数(LVEF)值均低于阴性组(P<0.05);阳性组心室前壁、后壁、下壁、室间壁纵向、径向、周向应变参数绝对值均低于阴性组(P<0.05);阳性组高敏肌钙蛋白I(hs-TnI)、脑钠肽(BNP)水平均高于阴性组(P<0.05);超声斑点技术结合血清心肌标志物诊断敏感度、准确度、阳性预测值、阴性预测值均高于常规超声诊断,诊断特异度高于常规超声(P<0.05)。结论:超声斑点技术结合血清心肌标志物一定程度上有助于检出酒精性心脏病,提高诊断准确性。Objective:To investigate the diagnostic value of ultrasound speckle technique combined with serum myocardial markers for alcoholic heart disease.Method:One hundred and twelve patients who consumed a lot of alcohol for a long time in Shenzhen Mental Health Center from March 2019 to September 2022 were selected and all received conventional ultrasound examination,ultrasound speckle technique and serum myocardial markers examination,the diagnostic efficacy of ultrasound speckle technique combined with serum myocardial markers for alcoholic heart disease were analyzed.Result:Alcoholic heart disease was detected in 45 of 112 patients(40.18%);the values of left atrial internal diameter(LAD),maximum late diastolic flow velocity(A),left ventricular enddiastolic internal diameter(LVEDD),left ventricular end-systolic internal diameter(LVESD) in the positive group were higher than those in the negative group,and the values of maximum early diastolic blood flow velocity(E),early diastolic maximum blood flow velocity/late diastolic maximum blood flow velocity(E/A),stroke volume(SV) and left ventricular ejection fraction(LVEF) in the positive group were lower than those in the negative group(P<0.05);the absolute values of longitudinal,radial and circumferential strain parameters of anterior wall,posterior wall,inferior wall and interventricular wall in positive group were lower than those in negative group(P<0.05);the levels of high-sensitivity troponin I(hs-TnI) and brain natriuretic peptide(BNP) in positive group were higher than those in negative group(P<0.05);the diagnostic sensitivity,accuracy,positive predictive value and negative predictive value of ultrasound speckle technique combined with serum myocardial markers were higher than those of conventional ultrasound diagnosis,and the diagnostic specificity was higher than that of conventional ultrasound(P<0.05).Conclusion:Ultrasound speckle technique combined with serum myocardial markers can help detect alcoholic heart disease to a certain extent and improve the diagnos

关 键 词：酒精性心脏病 超声斑点技术 血清心肌标志物 

分 类 号：R541.9[医药卫生—心血管疾病]