Keap1-Nrf2/ARE信号通路介导的昆虫抗药性机制的研究进展  

Research Progress on The Mechanism of Insect Resistance Mediated by Keap1-Nrf2/ARE Signaling Pathway

作　　者：曾苑芳 来有鹏 ZENG Yuan-fang;LAI You-peng(Qinghai University,Xining Qinghai 810016,China;Key Laboratory of Integrated Pest Management in Agriculture,Xining Qinghai 810016,China)

机构地区：[1]青海大学,青海西宁810016 [2]青海省农业有害生物综合治理重点实验室,青海西宁810016

出　　处：《青海农林科技》2022年第4期56-59,共4页Science and Technology of Qinghai Agriculture and Forestry

摘　　要：杀虫剂大量高频次的使用是昆虫抗药性产生的主要原因之一。Keap1-Nrf2/ARE信号通路是抵御细胞氧化应激和异生物质反应的关键通路,与昆虫代谢抗性的产生有关。本文综述了该信号通路调控下游代谢酶的研究进展,为进一步研究昆虫抗性机制提供参考。The high frequency use of pesticides is one of the main reasons for insect resistance.Keap1-Nrf2/ARE signaling pathway is the key pathway to resist cell oxidative stress and xenobiotic reaction, which is related to the generation of insect metabolic resistance.In this paper, the research progress of this signaling pathway regulating downstream metabolic enzymes is reviewed, which will provide a reference for further study of insect resistance mechanism.

关 键 词：抗药性 Keap1-Nrf2/ARE信号通路 调控 

分 类 号：S481.4[农业科学—农药学]