左房容积指数用于预测心房颤动患者射频消融后复发的meta分析  

Left atrial volume index predicts atrial fibrillation recurrence after radiofrequency ablation:A meta-analysis

作　　者：李卫伟[1] 李亚男 Li Weiwei;Li Yanan(Department of Internal Medicine Emergency,Lanzhou University Second Hospital,Lanzhou 730000,China)

机构地区：[1]兰州大学第二医院急诊内科,甘肃兰州730000

出　　处：《临床荟萃》2022年第11期965-969,共5页Clinical Focus

摘　　要：目的评价左房容积指数(left atrial volume index,LAVI)用于预测心房颤动(atrial fibrillation,AF)患者射频消融术后复发的临床价值。方法计算机检索PubMed、the Cochrane Library、Web of Science、中国知网、中国生物医学文献数据库、维普数据库等,查找LAVI用于预测AF患者射频消融后复发的相关文献。采用STATA 12.0进行meta分析。结果共纳入13项研究1519例AF患者。Meta分析结果显示与AF射频消融后未复发患者相比,复发患者平均LAVI更高(SMD=2.51,95%CI:1.61~3.41,P=0.001),同时AF射频消融后未复发患者与复发患者LAV/LAVI两组间差异有统计学意义(OR=2.88,95%CI:2.68~3.10,P=0.001),提示AF患者接受射频消融术后密切监测LAVI变化可有效评估其术后复发的可能性。结论与AF射频消融术后未复发的患者相比,复发的患者平均LAVI更高,其可作为评估AF患者接受射频消融术后复发的有效指标。结论仍需更多多中心、大样本的随机对照试验验证。Objective To evaluate the clinical value of left atrial volume index(LAVI)in predicting recurrence in patients with atrial fibrillation(AF)after radiofrequency ablation(RFA).Methods PubMed,the Cochrane Library,Web of Science,China National Knowledge Internet(CNKI),China Biomedical Literature Database,VIP database,etc.were performed a computer search to find relevant literature regarding LAVI predicting recurrence after RFA in AF patients.Meta-analysis was performed using STATA 12.0.Results A total of 13 studies involving 1519 patients were eligibly included in this meta-analysis.The results of meta-analysis showed that patients with AF recurrence had a higher mean LAVI compared to patients with no recurrence(SMD=2.51,95%CI:1.61-3.41,P=0.001).After RFA,there was a statistically significant difference in LAV/LAVI between non-recurrence patients and recurrence patients(OR=2.88,95%CI:2.68-3.10,P=0.001).This suggested that close monitoring of LAVI changes after RFA could effectively assess the possibility of postoperative recurrence.Conclusion Patients with AF recurrence following RFA have a higher mean LAVI compared to patients with no recurrence,which can be used as an effective index to evaluate AF recurrence after RFA.The conclusion still needs to be verified by more multi-center,large-sample randomized controlled trials.

关 键 词：心房颤动 射频消融 复发 左房容积指数 

分 类 号：R541.75[医药卫生—心血管疾病]