COVID-19疫情背景下围生期孕产妇抑郁情绪相关影响因素分析  

Analysis of influencing factors of perinatal maternal depression during the COVID-19 pandemic

作　　者：雍瑞欣 柴红霞[2] 妥薇薇 陈丹丹 赵东荣 Yong Ruixin;Chai Hongxia;Tuo Weiwei;Chen Dandan;Zhao Dongrong(First School of Clinical Medical,Lanzhou University,Lanzhou 730099,Gansu Province,China;Department of Obstetrics,First Hospital of Lanzhou University,Lanzhou 730013,Gansu Province,China;Department of Obstetrics,Lanzhou Third People′s Hospital,Lanzhou 730050,Gansu Province,China)

机构地区：[1]兰州大学第一临床医学院,兰州730099 [2]兰州大学第一医院产科,兰州730013 [3]兰州市第三人民医院产科,730050

出　　处：《中华妇幼临床医学杂志（电子版）》2022年第5期591-598,共8页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

基　　金：国家级大学生科研创新项目(202210730176);兰州大学大学本科生科研创新项目(20200060032);兰州大学大学本科生科研创新项目(20220060099);兰州市卫生健康科技发展项目(2019-023);兰州市人才创新创业项目(2020-RC-75)。

摘　　要：目的探讨新型冠状病毒疾病(COVID-19)疫情背景下围生期孕产妇(孕龄为28孕周至产后7 d)抑郁情绪的发生情况及其相关影响因素。方法采用随机抽样法,根据兰州市某三甲医院产科门诊及住院部就诊的围生期孕产妇的就诊号,随机抽取COVID-19疫情暴发期(2020年4月1日至8月31日)的71例孕产妇;同时选取COVID-19疫情常态化时期(2021年4月1日至8月31日),在同一医院产科门诊及住院部就诊的与疫情暴发期年龄匹配的71例围生期孕产妇为研究对象。根据《爱丁堡产后抑郁量表》(EPDS)筛查这142例孕产妇的抑郁风险得分,将其分为抑郁组(n=64,EPDS得分≥9分)和非抑郁组(n=78,EPDS得分<9分)。对2组受试组采取线上、线下方式填写本研究自行设计的《受试者一般资料调查问卷》,再采用EPDS、《社会支持评定量表》(SSRS)调查社会对其支持情况。采用多因素非条件logistic回归分析导致围生期孕产妇抑郁情绪影响因素。本研究遵循的程序符合2013年新修订的《世界医学协会赫尔辛基宣言》要求,并与所有受试者本人签署临床研究知情同意书。结果①纳入本研究142例孕产妇的抑郁情绪检出率为45.1%(64/142)。2组孕产妇受教育程度和成长环境构成比比较,差异均有统计学意义(P<0.05)。②SSRS各维度得分结果显示,抑郁组孕产妇的抑郁症支持利用度得分,显著低于非抑郁组[(6.6±1.2)分vs(7.8±1.6)分],并且差异有统计学意义(t=4.72,P<0.001)。③2组孕产妇的SSRS结果中,SSRS总分、社区医疗服务中心支持程度这2个条目构成比比较,差异有统计学意义(χ^(2)=12.26、11.56,P=0.002、0.009)。④多因素非条件logistic回归分析结果显示,受教育程度、成长环境、SSRS总分,均为孕产妇抑郁情绪发生的影响因素。其中,成长环境为农村(OR=2.397,95%CI:1.012~5.675,P=0.047)和较低受教育水平(受教育程度为高中及中专)(OR=3.929,95%CI:1.046~14.762,P=0.043),�Objective To investigate incidence and social factors of depression in perinatal pregnant women under corona virus disease 2019(COVID-19)pandemic.Methods A total of 71 pregnant women were randomly selected according to their medical card number from April 1,2020 to August 31,2020 in the obstetric department outpatient and inpatient of a grade A class 3 hospital in Lanzhou during the COVID-19 outbreak.Then,a total of 71 pregnant women who were treated in the obstetrics department outpatient and inpatient of the same hospital during the normalized COVID-19 pandemic period from April 1 to August 31,2021 were selected into this study.According to the Edinburgh Postnatal Depression Scale(EPDS),pregnant women were divided into depression group(n=64,EPDS score≥9)and non-depression group(n=78,EPDS score<9).The general information of the subjects was investigated by filling in the electronic questionnaire or manually filling in the paper version of the questionnaire,and then the EPDS and Social Support Rating Scale(SSRS)were used to investigate their social support information.Multivariate unconditional logistic regression analysis was used to analyze the influencing factors of depression in perinatal pregnant women.The procedures followed in this study were in accordance with the newly revised World Medical Association Declaration of Helsinki in 2013,and informed consent for clinical study was signed with all subjects.Results①Among 142 pregnant women,the detection rate of depression was 45.1%(64/142).There were significant differences in education level and growth environment between two groups(P<0.05).②The scores of each dimension of SSRS in two groups showed that the score of support utilization of depression group was lower than that of the non-depression group[(6.6±1.2)scores vs(7.8±1.6)scores],and the difference was statistically significant(t=4.72,P<0.001).③Among the social related factors of pregnant women in two groups,there were statistically significant differences in the composition ratio of the tota

关 键 词：孕妇 产妇 围产期 新型冠状病毒疾病 抑郁 社会支持 社会心理支持系统 

分 类 号：R714.7[医药卫生—妇产科学]